Results 31 to 40 of about 577,108 (265)

The Effect of Erythropoietin and Its Derivatives on Ischemic Stroke Therapy: A Comprehensive Review

Frontiers in Pharmacology, 2022
Numerous studies explored the therapeutic effects of erythropoietin (EPO) on neurodegenerative diseases. Few studies provided comprehensive and latest knowledge of EPO treatment for ischemic stroke.
Yuanyuan Ma, Zhiyuan Zhou, Guo-Yuan Yang, Jing Ding, Xin Wang, Xin Wang   +5 more
doaj   +1 more source

Role of excretory graft function for erythropoietin formation after renal transplantation [PDF]

, 1990
To examine the role of renal excretory function for erythropoietin (EPO) formation we have determined the kinetics of plasma immunoreactive EPO (irEPO) in patients with end-stage renal disease undergoing renal allotransplantation (RTX).
V. KLIEM, U. FREI, Bauer, Christian, C. BAUER, V. KLIEM, Koch, K. M., K. M. KOCH, Kurtz, Armin, Frei, U., A. KURTZ, Kliem, V., Eckardt, Kai-Uwe, K.‐U. ECKARDT, K.-U. ECKARDT   +13 more
core   +1 more source

Localization of Erythropoietin and Erythropoietin‐Receptor in Postimplantation Mouse Embryos [PDF]

Development, Growth & Differentiation, 1993
We used RT‐PCR (reverse transcription‐polymerase chain reaction) and immunocytochemical methods to demonstrate the presence of erythropoietin (Ep) and its receptor (EpR) in postimplantation mouse embryos from the egg‐cylinder to the unturned stage. Expression of mRNA for EpR was detected in total RNA from embryos and decidua in all these stages, but Ep
Yoshiko, Yasuda, Masaya, Nagao, Masaki, Okano, Seiji, Masuda, Ryuzo, Sasaki, Hiroyoshi, Konishi, Takashi, Tanimura   +6 more
openaire   +2 more sources

Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]

, 1993
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
A Zimmermann, K H Götz, Ratcliffe, P. J., Ratcliffe, Peter, Reinhart, WH, Götz, Karlheinz, Hamann, M., Götz, KH, M Hamann, A Kurtz, A Singh, Kurtz, A, Reinhart, W. H., Singh, A., Zimmermann, A., Kurtz, Armin, K U Eckardt, Hamann, M, Singh, A, Eckardt, KU, P J Ratcliffe, W H Reinhart, Zimmermann, A, Eckardt, Kai-Uwe   +23 more
core   +1 more source

Approaches to Manipulate Ephrin-A:EphA Forward Signaling Pathway

Pharmaceuticals, 2020
Erythropoietin-producing hepatocellular carcinoma A (EphA) receptors and their ephrin-A ligands are key players of developmental events shaping the mature organism. Their expression is mostly restricted to stem cell niches in adults but is reactivated in
Sarah Baudet, Johann Bécret, Xavier Nicol   +2 more
doaj   +1 more source

Serum immunoreactive erythropoietin of children in health and disease [PDF]

, 1990
Serum immunoreactive erythropoietin (siEPO) was determined in cord serum from neonates (n = 97, gestational age 36-43 weeks), in healthy children from birth to adolescence (n = 260) and in children with haematological (n = 30), renal (n = 10) and ...
Pohlandt, F., Vetter, U., Kurtz, Armin, Hartmann, W., Eckardt, Kai-Uwe, Burghardt, R.   +5 more
core   +1 more source

Mechanism of haematotoxicity induced by phenylhydrazine: a review

Journal of Applied Pharmaceutical Research, 2019
This work was carried out to show the effects of phenylhydrazine (PHZ) induced anaemic condition. Anaemic condition is defined as reduction in red blood cells (RBC) than normal number of red blood cells. The anti-anaemic activity can be studied using the
B R Shwetha, H S Siddalingaprasad, Shivukumar Swamy, N C Nagalakshmi, M G Hariprasad   +4 more
doaj   +1 more source

Characterisation of bovine leukocyte Ig-like receptors [PDF]

, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC, Singh, M, Allen, RL, Trowsdale, J, Laing, K, Butcher, P, Bhuju, S, Hogan, L, Vordermeier, M   +8 more
core   +4 more sources

Decline of erythropoietin formation at continuous hypoxia is not due to feedback inhibition [PDF]

, 1990
Serum erythropoietin (EPO) levels in response to hypoxia are known to decline before an increase in blood oxygen carrying capacity. To define the possible mechanisms underlying this phenomenon, we have investigated 1) how renal EPO mRNA content and EPO ...
J. Dittmer, Neumann, R., Eckardt, K. U., Bauer, C., A. Kurtz, Christian Bauer, Dittmer, J., Armin Kurtz, Jurgen Dittmer, K. U. Eckardt, Kai-uwe Eckardt, Kurtz, Armin, R. Neumann, C. Bauer, Rainer Neumann   +14 more
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources