Results 11 to 20 of about 134,430 (166)
Staphylococcus aureus can use an alternative pathway to be internalized by osteoblasts in absence of β1 integrins [PDF]
Scientific ReportsStaphylococcus aureus main internalization mechanism in osteoblasts relies on a tripartite interaction between bacterial fibronectin-binding proteins, extracellular matrix soluble fibronectin, and osteoblasts’ β1 integrins.
Léo-Paul Tricou +7 more
doaj +2 more sources
Cells, 2022 The microenvironment of tumors is characterized by structural changes in the fibronectin matrix, which include increased deposition of the EDA isoform of fibronectin and the unfolding of the fibronectin Type III domains.
Anthony Ambesi +2 more
doaj +1 more source
Vietnam Journal of Science, Technology and Engineering, 2022 Fibronectin is an abundant and ubiquitous extracellular matrix component that regulates a wide range of cell functions by directly interacting with cell surface integrin receptors.
Khon Huynh
doaj +1 more source
Frontiers in Medicine, 2022 Atherosclerosis is the major cause of cardiovascular disease that is characterized by plaque formation in the blood vessel wall. Atherosclerotic plaques represent sites of chronic inflammation with diverse cell content that is shifted toward the ...
Daria M. Potashnikova +9 more
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Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin [PDF]
, 2016 Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the extracellular matrix, yet the mechanisms behind this phenomenon are unclear.
Barton, William A. +3 more
core +11 more sources
eLife, 2021 Nanometer-scale properties of the extracellular matrix influence many biological processes, including cell motility. While much information is available for single-cell migration, to date, no knowledge exists on how the nanoscale presentation of ...
Jacopo Di Russo +5 more
doaj +1 more source
Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors. [PDF]
PLoS ONE, 2015 Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth.
Patrick A Murphy +2 more
doaj +1 more source
Fibronectin and Its Receptors in Hematopoiesis
Cells, 2020 Fibronectin is a ubiquitous extracellular matrix protein that is produced by many cell types in the bone marrow and distributed throughout it. Cells of the stem cell niche produce the various isoforms of this protein.
Franziska Wirth +3 more
doaj +1 more source
Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. [PDF]
PLoS ONE, 2008 Fibronectin polymerization is essential for the development and repair of the extracellular matrix. Consequently, deciphering the mechanism of fibronectin fibril formation is of immense interest.
Elaine P S Gee +2 more
doaj +1 more source
Wnt5A modulates integrin expression in a receptor-dependent manner in ovarian cancer cells
Scientific Reports, 2021 Wnt5A signals through various receptors that confer versatile biological functions. Here, we used Wnt5A overexpressing human ovarian SKOV-3 and OVCAR-3 stable clones for assessing integrin expression, cell proliferation, migration, invasion, and the ...
Vajihe Azimian-Zavareh +5 more
doaj +1 more source