Results 1 to 10 of about 2,384,030 (136)
Intra-accumbens baclofen, but not muscimol, increases second order instrumental responding for food reward in rats. [PDF]
PLoS ONE, 2012 Stimulation of either GABA(A) or GABA(B) receptors within the nucleus accumbens shell strongly enhances food intake in rats. However the effects of subtype-selective stimulation of GABA receptors on instrumental responses for food reward are less well ...
Kim G T Pulman +2 more
doaj +16 more sources
BMC Research Notes, 2012 Background GABA receptors are well known as the inhibitory receptors in the central nervous system and are also found in peripheral tissues. We have previously shown that GABA receptors are involved in lung development and fluid homeostasis. However, the
Zhao Chunling +5 more
doaj +2 more sources
Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes. [PDF]
PLoS ONE, 2012 γ-Aminobutyric acid (GABA) is the most prominent neuroinhibitory transmitter in the brain, where it activates neuronal GABA-A receptors (GABA-A channels) located at synapses and outside of synapses.
Suresh K Mendu +3 more
doaj +2 more sources
A Gut Feeling about GABA: Focus on GABAB receptors
Frontiers in Pharmacology, 2010 Gamma-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the body and hence GABA-mediated neurotransmission regulates many physiological functions, including those in the gastrointestinal (GI) tract.
Niall P Hyland, John F Cryan
doaj +2 more sources
Cells, 2022 Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABAA receptors on cerebrovascular endothelial cells ...
Sharon Negri +8 more
doaj +1 more source
Electrophysiology of ionotropic GABA receptors
Cellular and Molecular Life Sciences, 2021 GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal ...
Erwan Sallard +2 more
semanticscholar +1 more source
Pharmacological Effect of GABA Analogues on GABA-ϱ2 Receptors and Their Subtype Selectivity
Life, 2022 GABAϱ receptors are distinctive GABAergic receptors from other ionotropic GABAA and metabotropic GABAB receptors in their pharmacological, biochemical, and electrophysiological properties. Although GABA-ϱ1 receptors are the most studied in this subfamily,
Moawiah M. Naffaa +3 more
doaj +1 more source
Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. [PDF]
PLoS ONE, 2011 Together, acid-sensing ion channels (ASICs) and epithelial sodium channels (ENaC) constitute the majority of voltage-independent sodium channels in mammals. ENaC is regulated by a chloride channel, the cystic fibrosis transmembrane conductance regulator (
Xuanmao Chen +3 more
doaj +1 more source
The role of GABA in islet function
Frontiers in Endocrinology, 2022 Gamma aminobutyric acid (GABA) is a non-proteinogenic amino acid and neurotransmitter that is produced in the islet at levels as high as in the brain. GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD), of which the 65 kDa isoform (GAD65)
D. W. Hagan +6 more
semanticscholar +1 more source
Reproductive Medicine and Biology, 2023 Purpose Several widely used substances (e.g., some therapeutics or food supplements) can act on gamma‐aminobutyric acid (GABA) receptors, and we investigated whether the activation of these receptors could affect the preimplantation embryo.
Veronika Kovaříková +7 more
doaj +1 more source