Results 1 to 10 of about 2,475,949 (282)

Computational prediction of MicroRNAs targeting GABA receptors and experimental verification of miR-181, miR-216 and miR-203 targets in GABA-A receptor

open access: yesBMC Research Notes, 2012
Background GABA receptors are well known as the inhibitory receptors in the central nervous system and are also found in peripheral tissues. We have previously shown that GABA receptors are involved in lung development and fluid homeostasis. However, the
Zhao Chunling   +5 more
doaj   +2 more sources

Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes. [PDF]

open access: yesPLoS ONE, 2012
γ-Aminobutyric acid (GABA) is the most prominent neuroinhibitory transmitter in the brain, where it activates neuronal GABA-A receptors (GABA-A channels) located at synapses and outside of synapses.
Suresh K Mendu   +3 more
doaj   +2 more sources

Evidence for a GABAergic system in rodent and human testis: Local GABA production and GABA receptors [PDF]

open access: yesNeuroendocrinology, 2003
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors.
Calandra, Ricardo S.   +7 more
core   +3 more sources

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

open access: yesMolecular Pain, 2009
Background γ-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Bettler Bernhard   +6 more
doaj   +4 more sources

A Gut Feeling about GABA: Focus on GABAB receptors

open access: yesFrontiers in Pharmacology, 2010
Gamma-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the body and hence GABA-mediated neurotransmission regulates many physiological functions, including those in the gastrointestinal (GI) tract.
Niall P Hyland, John F Cryan
doaj   +2 more sources

Intra-accumbens baclofen, but not muscimol, increases second order instrumental responding for food reward in rats. [PDF]

open access: yesPLoS ONE, 2012
Stimulation of either GABA(A) or GABA(B) receptors within the nucleus accumbens shell strongly enhances food intake in rats. However the effects of subtype-selective stimulation of GABA receptors on instrumental responses for food reward are less well ...
Kim G T Pulman   +2 more
doaj   +5 more sources

GABAA and GABAB Receptors Mediate GABA-Induced Intracellular Ca2+ Signals in Human Brain Microvascular Endothelial Cells

open access: yesCells, 2022
Numerous studies recently showed that the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), can stimulate cerebral angiogenesis and promote neurovascular coupling by activating the ionotropic GABAA receptors on cerebrovascular endothelial cells ...
Sharon Negri   +8 more
doaj   +1 more source

Electrophysiology of ionotropic GABA receptors

open access: yesCellular and Molecular Life Sciences, 2021
GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal ...
Erwan Sallard   +2 more
semanticscholar   +1 more source

Activation of GABA(A) receptors inhibits T cell proliferation

open access: yesPLoS ONE, 2021
Background The major sites for fast synaptic inhibition in the central nervous system (CNS) are ion channels activated by γ-aminobutyric acid (GABA). These receptors are referred as GABA(A) receptors (GABA(A)R). Recent evidence indicates a role of GABA(A)
E. Sparrow   +5 more
semanticscholar   +1 more source

Pharmacological Effect of GABA Analogues on GABA-ϱ2 Receptors and Their Subtype Selectivity

open access: yesLife, 2022
GABAϱ receptors are distinctive GABAergic receptors from other ionotropic GABAA and metabotropic GABAB receptors in their pharmacological, biochemical, and electrophysiological properties. Although GABA-ϱ1 receptors are the most studied in this subfamily,
Moawiah M. Naffaa   +3 more
doaj   +1 more source

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