Results 221 to 230 of about 449,457 (314)

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

SST interneurons facilitate dendritic calcium signaling via tonic activation of α5-GABA receptors. [PDF]

Neuron
Chiu CQ, Morse TM, AitOuares K, Panzera LC, Patel PA, Nani F, Knoflach F, Hernandez MC, Jadi M, Higley MJ.   +9 more
europepmc   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Functional signatures of de novo GABBR1 and GABBR2 variants associated with neurodevelopmental disorders. [PDF]

NPJ Genom Med
Stawarski M, Bielopolski N, Roitman I, Fridman K, Wald-Altman S, Eitel M, Hui B, Vulto-van Silfhout A, Stegmann APA, Chirita-Emandi A, Eason J, Bradshaw K, Darnell L, Kostrzewa G, Ploski R, Meurs R, Batté A, Antonarakis SE, Gassmann M, Bettler B.   +19 more
europepmc   +1 more source

Salivary biomarkers in sleep‐related disorders

Sleep Research, EarlyView.
Abstract The exploration of salivary biomarkers has emerged as a promising avenue in the diagnosis and management of sleep‐related disorders, such as obstructive sleep apnea (OSA), insomnia, and sleep deprivation. Saliva is a noninvasive biofluid that contains a wealth of biological markers, reflecting both local and systemic physiological changes ...
Chuan Xiang Li, Yi Wang, Ying Ni Lin, Jun Qi Lin, Ya Ru Yan, Xian wen Sun, Liu Zhang, Shi Qi Li, Ning Li, Qing Yun Li   +9 more
wiley   +1 more source

Gut-Brain Signaling in Parkinson's Disease: A Narrative Review. [PDF]

Int J Mol Sci
Ratajczyk K, Kaczorowska E, Wyka K, Tarasiuk-Zawadzka A, Fichna J, Gajos A.   +5 more
europepmc   +1 more source

Bias in, symbolic compliance out? GPT's reliance on gender and race in strategic evaluations

Strategic Management Journal, EarlyView.
Abstract Research summary Organizations are increasingly using large language models (LLMs) to support strategic evaluations. We examine whether and how these systems rely on gender and race. We asked GPT to evaluate identical startup pitches varying only the founder's name, shaping gender and race perceptions.
Tristan L. Botelho, Qingyang (Iris) Wang
wiley   +1 more source

Excitatory GABA receptors shape locomotor circuit organization in C. elegans. [PDF]

Sci Rep
Wang X, Mizuguchi K, Hashimoto K.
europepmc   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

Editorial: The interplay between GABA and glutamate in systems physiology and pathophysiology. [PDF]

Front Pharmacol
Rivera C, Lewis SJ.
europepmc   +1 more source