Results 251 to 260 of about 177,108 (289)

Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation. [PDF]

Sci Adv
Molinari M, Aaltonen A, Lieberman OJ, Sulzer D, Santini E, Borgkvist A.   +5 more
europepmc   +1 more source

Management strategies for burning mouth syndrome: a comprehensive review. [PDF]

J Oral Facial Pain Headache
Canfora F, Coppola N, Calabria E, Armogida NG, Mignogna MD, Spagnuolo G, Adamo D.   +6 more
europepmc   +1 more source

Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors. [PDF]

Int J Biol Sci
Kang JS, Baek JH, Park H, Rehman NU, Chung HJ, Lee DK, Oh S, Kim HJ.   +7 more
europepmc   +1 more source

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GABA-A Receptor Complex and Memory Processes

Medicinal Chemistry Reviews - Online, 2002
Considerable evidence has been provided these last years for the involvement of the GABAA receptor complex in memory processes. Compounds that enhance the action of GABA, such as benzodiazepines, impair memory processing. On the contrary, compounds that reduce the action of GABA, such as -CCM, pentylenetetrazol or picrotoxin, have the opposite action,
Georges, Chapouthier, Patrice, Venault
openaire   +2 more sources

GABA-A-Receptor Ligands of Flavonoid Structure

Current Topics in Medicinal Chemistry, 2002
This review describes the new research developments that have established the CNS-activity of some natural flavonoids. The properties of flavone, chrysin, apigenin and cirsiliol are described and a survey of the occurrence of ligands for the benzodiazepine binding site in the flavonoid field is attempted.
Mariel, Marder, Alejandro C, Paladini
openaire   +2 more sources

GABA-A Receptor Ligands and their Therapeutic Potentials

Current Topics in Medicinal Chemistry, 2002
The GABA(A) receptor system is implicated in a number of neurological diseases, making GABA(A) receptor ligands interesting as potential therapeutic agents. Only a few different classes of structures are currently known as ligands for the GABA recognition site on the GABA(A) receptor complex, reflecting the very strict structural requirements for GABA ...
Frølund, Bente, Ebert, Bjarke, Kristiansen, Uffe, Liljefors, Tommy, Krogsgaard-Larsen, Povl   +4 more
openaire   +3 more sources

GABAA receptor epilepsy mutations

Biochemical Pharmacology, 2004
Idiopathic generalized epilepsy (IGE) syndromes are diseases that are characterized by absence, myoclonic, and/or primary generalized tonic-clonic seizures in the absence of structural brain abnormalities. Although it was long hypothesized that IGE had a genetic basis, only recently have causative genes been identified.
Robert L, Macdonald, Martin J, Gallagher, Hua-Jun, Feng, Jingqiong, Kang   +3 more
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GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton

Nature, 1999
Type-A receptors for the neurotransmitter GABA (gamma-aminobutyric acid) are ligand-gated chloride channels that mediate inhibitory neurotransmission. Each subunit of the pentameric receptor protein has ligand-binding sites in the amino-terminal extracellular domain and four membrane-spanning regions, one of which forms a wall of the ion channel.
H, Wang, F K, Bedford, N J, Brandon, S J, Moss, R W, Olsen   +4 more
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