Results 31 to 40 of about 2,475,949 (282)

An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]

open access: yes, 2002
There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C.   +5 more
core   +1 more source

GABA Receptors: Pharmacological Potential and Pitfalls.

open access: yesCurrent pharmaceutical design, 2015
Gamma-amino butyric acid (GABA), the major inhibitory neurotransmitter in the mammalian central nervous system, plays a key role in the regulation of neuronal transmission throughout the brain, affecting numerous physiological and psychological processes.
M. J. Jembrek, J. Vlainić
semanticscholar   +1 more source

GABA-A and GABA-B Receptors in Filial Imprinting Linked With Opening and Closing of the Sensitive Period in Domestic Chicks (Gallus gallus domesticus)

open access: yesFrontiers in Physiology, 2018
Filial imprinting of domestic chicks has a well-defined sensitive (critical) period lasting in the laboratory from hatching to day 3. It is a typical model to investigate the molecular mechanisms underlying memory formation in early learning. We recently
Naoya Aoki   +7 more
doaj   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

open access: yes, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source

Huntington's disease leads to decrease of GABA-A tonic subunits in the D2 neostriatal pathway and their relocalization into the synaptic cleft

open access: yesNeurobiology of Disease, 2018
GABA is a widely distributed inhibitory neurotransmitter. GABA-A receptors are hetero-pentameric channels assembled in multiple combinations from 19 available subunits; this diversity mediates phasic and tonic inhibitory synaptic potentials. Whereas GABA-
Abraham Rosas-Arellano   +7 more
doaj   +1 more source

Intermittent Hypoxia Interferes with Autocrine Effects of GABA on Insulin Secretion in Postnatal Rodents—Implications for Pediatric Obstructive Sleep Apnea

open access: yesChildren, 2022
Gamma-amino butyric acid (GABA) is well known to help elevate pancreatic β cell vitality and insulin levels in blood. GABA works via a coupling with GABA receptors; thus, the concentration of GABAA receptors on the plasma membrane of β cells appears to ...
Eung-Kwon Pae   +2 more
doaj   +1 more source

Role of GABA and its receptors in anti-adipogenesis in cultured adipocytes [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2020
Health benefits of GABA and GABA-enriched foods via anti-obesity activity have been demonstrated in animals. However, the functional roles of GABA especially as non-neurotransmitter in adipocytes have not been thoroughly clarified.
Kanittaporn Trisat   +2 more
doaj   +1 more source

Emerging neurotrophic role of GABAB receptors in neuronal circuit development [PDF]

open access: yes, 2013
The proper development of highly organized structures in the central nervous system is a complex process during which key events – neurogenesis, migration, growth, differentiation, and synaptogenesis – have to take place in an appropriate manner to ...
Christophe Porcher, Jean-Luc Gaiarsa
core   +1 more source

Stimulation of TM3 Leydig cell proliferation via GABAA receptors: A new role for testicular GABA

open access: yesReproductive Biology and Endocrinology, 2004
The neurotransmitter gamma-aminobutyric acid (GABA) and subtypes of GABA receptors were recently identified in adult testes. Since adult Leydig cells possess both the GABA biosynthetic enzyme glutamate decarboxylase (GAD), as well as GABAA and GABAB ...
Krieger Annette   +4 more
doaj   +1 more source

The potential role of pancreatic γ-aminobutyric acid (GABA) in diabetes mellitus: A critical reappraisal

open access: yesInternational Journal of Preventive Medicine, 2021
Background: Diabetes mellitus (DM) is an endocrine disorder characterized by hyperglycemia, polyuria, polydipsia, and glucosuria. γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the central nervous system (CNS) of humans and other mammals.
Hayder M Al-Kuraishy   +5 more
doaj   +1 more source

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