Results 91 to 100 of about 2,388,695 (167)

Cocaine disrupts action flexibility via glucocorticoid receptors

open access: yesiScience
Summary: Many addictive drugs increase stress hormone levels. They also alter the propensity of organisms to prospectively select actions based on long-term consequences.
Michelle K. Sequeira   +4 more
doaj  

Hippocmapal Opioid Recptors Probably Mediating the Effects of Peripheal Corticosterone on Consolidation and Retreival of Spatial Memory in Rat [PDF]

open access: yesCell Journal, 2008
Objective: Strong evidence indicate that activity of glucocorticoid receptors is necessaryfor emotional memory processess and these effects probably are mediated by hipppocampal opioid receptors.
AA. Vafaei, A. Rashidy-Pour, AA. Sajadi
doaj  

Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus

open access: yesCell Reports, 2019
Summary: Glucocorticoids are lipid-soluble hormones that signal via the glucocorticoid receptor (GR), a ligand-dependent transcription factor. Circulating glucocorticoids derive from the adrenals, but it is now apparent that paracrine glucocorticoid ...
Matthew D. Taves   +4 more
doaj  

Acute stress enhances heterodimerization and binding of corticosteroid receptors at glucocorticoid target genes in the hippocampus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
K. Mifsud, J. Reul
semanticscholar   +1 more source

EFFECTS OF STRESS ON BEHAVIOUR AND SLEEP

open access: yesПраці Наукового товариства імені Шевченка. Медичні науки, 2017
Psychologists Yerkes and Dodson described already in 1908 the inverted-U shaped relationship between arousal and performance. When the level of arousal heightens, behavioural performance increases but only to a certain point.
Anton Coenen
doaj  

Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression

open access: yesCell Reports
Summary: The zona fasciculata (zF) in the adrenal cortex contributes to multiple physiological actions through glucocorticoid synthesis. The size, proliferation, and glucocorticoid synthesis characteristics are all female biased, and sexual dimorphism is
Fumiya Takahashi   +12 more
doaj  

Role of Prefrontal Cortex Glucocorticoid Receptors in Stress and Emotion

open access: yesBiological Psychiatry, 2013
J. McKlveen   +6 more
semanticscholar   +1 more source

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

open access: yesarXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

Glucocorticoid receptors in the prefrontal cortex regulate stress-evoked dopamine efflux and aspects of executive function

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
K. Butts   +3 more
semanticscholar   +1 more source

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