Results 11 to 20 of about 91,243 (312)

Glucocorticoid receptors modulate mitochondrial function A novel mechanism for neuroprotection [PDF]

Communicative & Integrative Biology, 2009
It has become increasingly clear that glucocorticoid (GC) signaling not only comprises classic nuclear receptor binding—that is, glucocorticoid receptors (GRs) to their response element in the nucleus—but also involves rapid, non-genomic efforts to ...
Jing Du, Bruce McEwen, Husseini K. Manji
doaj   +2 more sources

Glucocorticoid Receptors [PDF]

Journal of Biological Chemistry, 1974
Specific glucocorticoid receptors from chick embryonic neural retina are demonstratable as early as 6 days in ovo. The receptor also binds progesterone with high affinity.
Marc E. Lippman, Barbara O. Wiggert, Gerald J. Chader, E. Brad Thompson   +3 more
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Fibroblast growth factor 2 is necessary for the antidepressant effects of fluoxetine. [PDF]

PLoS ONE, 2018
Previous research has shown that fibroblast growth factor 2 protein (FGF2) can act as an anxiolytic and anti-depressive agent in rodents. Levels of hippocampal FGF2 and FGF2 receptors are decreased in post-mortem brains of individuals with mood disorders.
Stephanie Simard, Pragya Shail, Jessica MacGregor, Maha El Sayed, Ronald S Duman, Flora M Vaccarino, Natalina Salmaso   +6 more
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Genomic regulation of Krüppel-like-factor family members by corticosteroid receptors in the rat brain

Neurobiology of Stress, 2023
Hippocampal mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) mediate glucocorticoid hormone (GC) action in the hippocampus.
Clare L.M. Kennedy, Emily M. Price, Karen R. Mifsud, Silvia Salatino, Eshita Sharma, Simon Engledow, John Broxholme, Hannah M. Goss, Johannes M.H.M. Reul   +8 more
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Mixed-model QSAR at the glucocorticoid and liver X receptors [PDF]

, 2009
The presence of hormonally active compounds in the biosphere has become a worldwide environmental concern, and measures such as policy acts and regulations try to address the problem, both in Europe and in the United States.
Spreafico, Morena
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Localization of glucocorticoid receptors at postsynaptic membranes in the lateral amygdala [PDF]

, 2005
Glucocorticoids, released in high concentrations from the adrenal cortex during stressful experiences, bind to glucocorticoid receptors in nuclear and peri-nuclear sites in neuronal somata.
McEwen, B. S., LeDoux, J. E., Morrison, J. H., Johnson, Luke R., Farb, C.   +4 more
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The glucocorticoid receptor resource [PDF]

Nucleic Acids Research, 1996
The glucocorticoid receptor resource focuses on the structure-function relationships of the glucocorticoid receptor. As well as links to sequence and bibliographic databases via the World Wide Web, the database contains sequence comparisons of receptors from different species and source information for glucocorticoid receptor clones, probes, cell lines
Mark Danielsen, Elisabeth Martinez
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TAZ WW Domain-Mediated Regulation of Gluconeogenesis and Tumorigenesis in Hepatocellular Carcinoma through Interaction with the Glucocorticoid Receptor [PDF]

Endocrinology and Metabolism
Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, characterized by poor prognosis due to its high proliferative and invasive potential. Tumor metabolic reprogramming, particularly involving glucose metabolism, is essential
Hongxiang Huang, Jinhong Chen, Xingyu Tao, Peiyuan Zhong, Yanqiu Meng, Sujuan Peng, Wanying Luo, Zhiyong He, Shuai Luo, Xie Zhu, Zhihui Lu, Li Chen, Yangyang Liu   +12 more
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Corticosterone Induces HMGB1 Release in Primary Cultured Rat Cortical Astrocytes: Involvement of Pannexin-1 and P2X7 Receptor-Dependent Mechanisms

Cells, 2020
A major risk factor for major depressive disorder (MDD) is stress. Stress leads to the release of high-mobility group box-1 (HMGB1), which in turn leads to neuroinflammation, a potential pathophysiological basis of MDD.
Kazue Hisaoka-Nakashima, Honami Azuma, Fumina Ishikawa, Yoki Nakamura, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Yoshihiro Nakata, Norimitsu Morioka   +9 more
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Temporal and spatial dynamics of corticosteroid receptor down-regulation in rat brain following social defeat [PDF]

, 2001
The experiments explored the nature and time course of changes in glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) binding in homogenates of various brain regions and pituitary of male Wistar rats following social defeat stress.
Horváth, K.M., Bohus, B., Bohus, B, Bauke Buwalda, Nyakas, C, Felszeghy, K., Felszeghy, K, Béla Bohus, Klára Felszeghy, Horváth, Katalin M.,, Koolhaas, J M, Buwalda, B, Boer, Sietse F. de,, Nyakas, Csaba,, Csaba Nyakas, Katalin M Horváth, de Boer, S.F., Felszeghy, Klára,, Koolhaas, J.M., Sietse F de Boer, Koolhaas, Jaap M.,, Nyakas, C., Buwalda, Bauke,, Horváth, K M, Buwalda, B., Bohus, Béla,, Jaap M Koolhaas   +26 more
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