Results 271 to 280 of about 2,876,830 (353)

Glucocorticoids Improve in Vitro Mouse Oocyte Competence by Mimicking the Physiological Pre-Ovulatory Environment. [PDF]

Reprod Med Biol
Akter S, Yamanaka T, Okamoto A, Miraz MFH, Shimada M.   +4 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Alk-Fam150b (augmentor α) expression in the paraventricular nucleus of the mouse hypothalamus at molecular resolution, and its sensitivity to acute stress. [PDF]

J Neuroendocrinol
Gueissaz L, Sideromenos S, Tretiakov EO, Schnell R, Harkany T.   +4 more
europepmc   +1 more source

Anti-aging effects of the adrenal androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate: mechanisms of action and beneficial effects in older people. [PDF]

Endocr J
Nawata H, Yanase T, Morohashi KI, Nomura M, Muta K.   +4 more
europepmc   +1 more source

Dissecting the role of mineralocorticoid receptors in binge-like alcohol drinking in mice: Finerenone as a potential pharmacotherapy. [PDF]

Psychopharmacology (Berl)
Wilkinson CS, Bruns N, Pince CL, McGinn MA, Farokhnia M, Leggio L, Vendruscolo LF.   +6 more
europepmc   +1 more source

Peri-Transfer Glucocorticoid Therapy in Oocyte-Donation IVF Bridging the Immunological Gap. [PDF]

Int J Mol Sci
Voros C, Chatzinikolaou F, Papadimas G, Polykalas S, Mavrogianni D, Koulakmanidis AM, Athanasiou D, Kanaka V, Bananis K, Athanasiou A, Athanasiou A, Papapanagiotou I, Tsimpoukelis C, Karpouzos A, Daskalaki MA, Kanakas N, Theodora M, Thomakos N, Antsaklis P, Loutradis D, Daskalakis G.   +20 more
europepmc   +1 more source

Chronic stress-related neuroendocrine mediators and ovarian cancer. [PDF]

Discov Oncol
Du H, Yu G, Hu R, Du J, Liu C.
europepmc   +1 more source

Heterogeneity of lymphoid cells in PBMCs in the acute phase of SFTS: Single-cell transcriptome profiling. [PDF]

J Biomed Res
Zhao J, Xu R, Zhou T, Jin K, Zhu J, Zhang J, Han Y, Liu X, Lu D, Wang C, Qian J, Wang C, Li J.   +12 more
europepmc   +1 more source

Interleukin-35 as a key immunoregulatory mediator in steroid-hyporesponsive severe asthma. [PDF]

Front Immunol
Al-Matouq J, Khalid Salah Al-Sheakly B, Saheb Sharif-Askari N, Halwani R, Saheb Sharif-Askari F.   +4 more
europepmc   +1 more source

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Glucocorticoid receptor blockers

Pituitary, 2022
Mifepristone is the only glucocorticoid receptor antagonist currently approved for the treatment of Cushing's syndrome. Although originally developed as an abortifacient due to its blockade of the progesterone receptor, a number of case reports documented its efficacy as a glucocorticoid receptor blocker going back to 1985. The SEISMIC trial, published
openaire   +2 more sources