Results 71 to 80 of about 2,388,695 (167)
Biology of Sex Differences, 2013 Stress-related psychiatric disorders, such as unipolar depression and post-traumatic stress disorder (PTSD), occur more frequently in women than in men.
Bangasser Debra A
doaj +1 more source
N-terminal domain Increases Activation of Elephant Shark Glucocorticoid and Mineralocorticoid Receptors [PDF]
arXiv, 2019 Cortisol, corticosterone and aldosterone activate full-length glucocorticoid receptor (GR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Activation by aldosterone a mineralocorticoid, indicates partial divergence of elephant shark GR from the MR.
arxiv
Molecular Endocrinology, 2005 Glucocorticoids (Gc) act through the glucocorticoid receptor (GR) to enhance or repress transcription of glucocorticoid-responsive genes depending on the promoter and cellular context.
C. Martens +4 more
semanticscholar +1 more source
Existence and stability analysis of solutions for a ultradian glucocorticoid rhythmicity and acute stress model [PDF]
arXiv, 2019 The hypothalamic pituitary adrenal (HPA) axis responds to physical and mental challenge to maintain homeostasis in part by controlling the body's cortisol level. Dysregulation of the HPA axis is implicated in numerous stress-related diseases. For a structured model of the HPA axis that includes the glucocorticoid receptor but does not take into account
arxiv
Detection in Molecular Communications with Ligand Receptors under Molecular Interference [PDF]
arXiv, 2020 Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to transfer information among bio-nano devices. In this paper, we focus on the detection problem for biological MC receivers employing ligand receptors to infer the transmitted messages encoded into the concentration of molecules, i.e., ligands.
arxiv
Cell Reports, 2018 Summary: Steroid hormone receptors are simultaneously active in many tissues and are capable of altering each other’s function. Estrogen receptor α (ER) and glucocorticoid receptor (GR) are expressed in the uterus, and their ligands have opposing effects
Jeffery M. Vahrenkamp +10 more
doaj
Glucocorticoid receptor signaling in the brain and its involvement in cognitive function
Neural Regeneration ResearchThe hypothalamic–pituitary–adrenal axis regulates the secretion of glucocorticoids in response to environmental challenges. In the brain, a nuclear receptor transcription factor, the glucocorticoid receptor, is an important component of the hypothalamic ...
Chonglin Su +5 more
doaj +1 more source
Structure and dynamics of dynorphin peptide and its receptor [PDF]
arXiv, 2019 Dynorphin is a neuropeptide involved in pain, addiction and mood regulation. It exerts its activity by binding to the kappa opioid receptor (KOP) which belongs to the large family of G-protein coupled receptors. The dynorphin peptide was discovered in 1975, while its receptor was cloned in 1993.
arxiv
The expression of the ACTH receptor
Brazilian Journal of Medical and Biological Research, 2000 Adrenal glucocorticoid secretion is regulated by adrenocorticotropic hormone (ACTH) acting through a specific cell membrane receptor (ACTH-R). The ACTH-R is a member of the G protein superfamily-coupled receptors and belongs to the subfamily of ...
L.L.K. Elias, A.J.L. Clark
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Biochemical Journal, 2002 We performed a comparative analysis of the effect of high-mobility group box protein 1 (HMGB1) on DNA binding by the DNA-binding domains (DBDs) of the androgen, glucocorticoid, progesterone and mineralocorticoid receptors. The affinity of the DBDs of the
G. Verrijdt +4 more
semanticscholar +1 more source