Results 191 to 200 of about 183,883 (256)

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Valorisation of Edible Mushroom By-Products as Natural Flavour Enhancers in Plant-Based Foods: Mechanisms, Sensory Profiles, and Industrial Translation. [PDF]

Foods
Edkaidek H, Dahiya D, Nigam PS.
europepmc   +1 more source

A biophysically grounded model of glutamatergic synaptic transmission integrating glutamate transport, receptor kinetics, and electrotonic effects. [PDF]

J Comput Neurosci
Chizhov AV, Malkin SL, Khachatryan DN, Zaitsev AV.   +3 more
europepmc   +1 more source

The sleep-wake cycle: molecular mechanisms, disorders, and therapeutic targets in the context of energy metabolism. [PDF]

Signal Transduct Target Ther
Li JK, Wang RY, Meng XY, Kang JS.
europepmc   +1 more source

Phytochemicals with potential NMDAR-inhibitory activities: a review of neuroprotective mechanisms against excitotoxicity. [PDF]

Saudi Pharm J
Alamoudi AJ.
europepmc   +1 more source