Results 241 to 250 of about 294,096 (332)

The Brain Fatigue Syndrome-Symptoms, Probable Definition, and Pathophysiological Mechanisms. [PDF]

J Clin Med
Johansson B, Rönnbäck L.
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity. [PDF]

Cells
Paiva BS, Neves D, Tomé D, Costa FJ, Bruno IC, Trigo D, Silva RM, Almeida RD.   +7 more
europepmc   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation

ESC Heart Failure, EarlyView.
The METAB‐HTX trial is a prospective cohort study, evaluating cardiac and systemic metabolism among heart transplant recipients. Myocardial function, energetic and metabolism, allograft vasculopathy, allograft rejection, glucometabolism, lipometabolism, liver‐ and kidney function, leucocyte signatures and thromboinflammation will be evaluated ...
Amin Polzin, Daniel Scheiber, Fabian Voss, Jean Haurand, Elric Zweck, Daniel Oehler, Oliver Maier, Mareike Cramer, Maximilian Spieker, Constanze Moos, Ursala Tokhi, David Naguib, Philipp Mourikis, Marcel Benkhoff, Robert Wagner, Michael Roden, Heinz‐Peter Schultheiss, Sascha Dietrich, Hug Aubin, Udo Boeken, Artur Lichtenberg, Malte Kelm   +21 more
wiley   +1 more source

Making cells inter-connected for signaling communication: a developmental view of cytonemes. [PDF]

Cell Commun Signal
Ma J, Yu H, Yao S, Yan Y, Gu Z, Wang Z, Huang H, Chen D.   +7 more
europepmc   +1 more source

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Glutamate gradually elevates [Zn²⁺]_i via the CaM-CaMKII-NOS cascade in primary cultured rat embryonic cortical neurons. [PDF]

Sci Rep
Tseng HC, Wang YS, Pan CY.
europepmc   +1 more source

The Influence of Topiramate on Morphine Dependence in Mice. [PDF]

Biomolecules
Pysiewicz A, Mazur A, Kotlińska J, Baranowska-Bosiacka I, Fronc K, Łupina M, Kruk-Słomka M, Listos J.   +7 more
europepmc   +1 more source

Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson's disease: a systematic review. [PDF]

Front Aging Neurosci
Ishaq S, Shah IA, Lee SD, Wu BT.
europepmc   +1 more source