Results 261 to 270 of about 2,744,319 (336)

Impaired modulation of the trigeminal caudal nucleus by the locus coeruleus in diabetic mice: the role of GABAergic and glycinergic neurons. [PDF]

Front Neuroanat
Mesa-Lombardo A, García-Magro N, Nuñez A, Martin YB.   +3 more
europepmc   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

Novel octapeptide containing the RGD sequence as a potential anti-SARS-CoV-2 agent: design, synthesis, and theoretical studies. [PDF]

Amino Acids
Lemos R, Ortiz O, Almagro L, Makowski K, Rodríguez H, Albericio F, Suarez M.   +6 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Blocking extracellular glycine uptake mediated by GlyT1 mitigates protoporphyria. [PDF]

J Clin Invest
Liesa M.
europepmc   +1 more source

Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements. [PDF]

Sci Adv
Abbott JA, Kim J, Liu B, Popescu GK, Gouaux E, Jalali-Yazdi F.   +5 more
europepmc   +1 more source

Dynamics and Interplay of the Binding Pockets in the Glycine Receptor. [PDF]

J Chem Inf Model
Xue G, Clark JA, Kemble-Diaz C, Crnjar A, Molteni C.   +4 more
europepmc   +1 more source

Epitope analysis of an anti-mouse CCR1 monoclonal antibody S15040E using flow cytometry. [PDF]

Biochem Biophys Rep
Okada A, Suzuki H, Arimori T, Tanaka T, Kaneko MK, Kato Y.   +5 more
europepmc   +1 more source

Clioquinol "<i>Sweetens the Pot</i>" for Drug-Resistant Epilepsy-With an After Taste. [PDF]

Epilepsy Curr
Scharfman HE.
europepmc   +1 more source