Results 261 to 270 of about 3,076,380 (339)

An emerging role for synaptic Zn²⁺ in substance use disorders. [PDF]

Pharmacol Ther
Solis O, Curry FP, Frangos ZJ, Dunne W, Schoenborn I, Lauer A, Gomez JL, Ventriglia EN, Bonaventura J, Michaelides M.   +9 more
europepmc   +1 more source

Lysyl Oxidase Reduces Neutrophil Extravasation in Response to P. aeruginosa in an Infection‐on‐a‐Chip Model

Advanced NanoBiomed Research, EarlyView.
Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo, Tanvi Patil, Josephine Fouts, Eric L. Ginter, Margaret Radke, Hannah K. Weppner, Justin M. Owens, Laurel E. Hind   +7 more
wiley   +1 more source

Clonidine Inhibits Interictal-like Epileptiform Events in Prefrontal Cortex Pyramidal Neurons. [PDF]

Int J Mol Sci
Kołba W, Herbst D, Szulczyk B.
europepmc   +1 more source

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Microbial transformation of secondary bile acids: roles in gut ecology and autoimmune diseases. [PDF]

Front Immunol
Ren L, Li M, Wu L, Lin Z, Chen A.
europepmc   +1 more source

Intestinal amino acid metabolic response and its roles in inflammatory bowel disease. [PDF]

Cell Commun Signal
Niu Y, Wang F, Liu C, Liu Z, Hu X.
europepmc   +1 more source

Cryo-EM of autoantibody-bound NMDA receptors reveals antigenic hotspots in an active immunization model of anti-NMDAR encephalitis. [PDF]

Sci Adv
Kim J, Jalali-Yazdi F, Jones BE, Westbrook GL, Gouaux E.   +4 more
europepmc   +1 more source

Efficacy and safety of μ1-opioid receptor agonist (Taphalgin®) for emergency analgesia in outpatient practice. [PDF]

Saudi J Anaesth
Voloshin AG, Avetisova KN, Smirnova NV.
europepmc   +1 more source

Intranasal delivery of the NMDA receptor antagonist MK-801 attenuates ultra-acute excitotoxic neurochemical responses after concussion in rats: comparative pharmacological evaluation against ketamine. [PDF]

Front Pharmacol
Masse I, Moquin L, Bouchard C, Legroux L, Gratton A, De Beaumont L.   +5 more
europepmc   +1 more source