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Hijacking of GABAA Receptors by Mutant Glycine Receptors
Trends in Molecular Medicine, 2019Startle disease results from mutations in genes encoding inhibitory GlyR α1 and β subunits or the presynaptic glycine transporter GlyT2. However, the most effective therapies are benzodiazepines that potentiate inhibitory GABAAR function. A recent publication by Zou et al.
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Science Signaling, 2003
Semiconductor quantum dots (QDs) have recently emerged as probes with the potential to revolutionize fluorescence imaging. Dahan et al. have now detected single QD-tagged glycine receptors in living cultured spinal neurons.
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Semiconductor quantum dots (QDs) have recently emerged as probes with the potential to revolutionize fluorescence imaging. Dahan et al. have now detected single QD-tagged glycine receptors in living cultured spinal neurons.
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Regulation of Excitation by Glycine Receptors
2007Our knowledge of glycine receptor (GlyR) regulation of excitation has advanced significantly in recent years. GlyRs are widespread in the CNS, are heterogeneous, and undergo developmental changes. Activation of GlyRs of immature neurons induces outflow of Cl( - ), membrane depolarization, neuronal excitation, calcium influx, and transmitter release, in
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Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth
Cell Metabolism, 2022Dzmitry Mukha +2 more
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Mechanism of gating and partial agonist action in the glycine receptor
Cell, 2021Hongtao Zhu +2 more
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Glycine: The Smallest Anti-Inflammatory Micronutrient
International Journal of Molecular Sciences, 2023Fausto Sanchez-Munoz +2 more
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