Results 161 to 170 of about 51,381 (211)

Reprogramming the melanoma tumor immune microenvironment via combinatorial signal 2/3 gene delivery. [PDF]

open access: yesJ Immunother Cancer
Luly KM   +11 more
europepmc   +1 more source

Detection of the granulocyte colony-stimulating factor receptor using biotinylated granulocyte colony-stimulating factor: presence of granulocyte colony-stimulating factor receptor on CD34-positive hematopoietic progenitor cells

Research in Experimental Medicine, 1992
Granulocyte colony-stimulating factor (G-CSF) was linked to NHS-biotin to yield biotinylated G-CSF (b-G-CSF), which retained the ability to stimulate colony formation by normal bone marrow (BM) cells in methylcellulose. The use of streptavidin-phycoerythrin conjugate in conjunction with flow cytometry demonstrated that the binding of biotinylated G-CSF
K, Shimoda   +3 more
openaire   +2 more sources

Granulocyte-macrophage colony-stimulating factor mimicry and receptor interactions

Immunologic Research, 1994
Development of small molecular mimics of larger polypeptide ligands is an important approach to pharmacophore design. One strategy for the development of such mimics is analysis of alternative ligands that bind to the same site as the native ligand. These allow examination of the structural and chemical constraints for binding within the setting of ...
J M, Von Feldt   +5 more
openaire   +2 more sources

Granulocyte colony-stimulating factor receptor: Structure and function

2001
Publisher Summary This chapter describes the granulocyte colony-stimulating factor receptor (G-CSF-R) as a member of the type I cytokine receptor superfamily. Members of this family contain a structurally conserved module in their extracellular domains and include the receptors for other CSFs and interleukins.
S, Akbarzadeh, J E, Layton
openaire   +2 more sources

Expression cloning of a receptor for murine granulocyte colony-stimulating factor

Cell, 1990
Two cDNAs encoding the receptor for murine granulocyte colony-stimulating factor (G-CSF) were isolated from a CDM8 expression library of mouse myeloid leukemia NFS-60 cells, and their nucleotide sequences were determined. Murine G-CSF receptor expressed in COS cells could bind G-CSF with an affinity and specificity similar to that of the native ...
R, Fukunaga   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy