Results 31 to 40 of about 2,977,129 (352)
Animals, 2021 The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo +10 more
doaj +1 more source
BRET biosensor analysis of receptor tyrosine kinase functionality
Frontiers in Endocrinology, 2013 Bioluminescence resonance energy transfer (BRET) is an improved version of earlier resonance energy transfer technologies used for the analysis of biomolecular protein interaction.
Sana eSiddiqui +4 more
doaj +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2023 Hyaluronic acid (HA) has the capability to influence dentin niche which is important in regenerative process. The CD44 as a specific receptor of HA was found to be related to dentin mineralization process. Meanwhile, transforming growth factor β1 (TGF-β1)
Dini Asrianti Bagio +5 more
doaj +1 more source
Triple negative breast cancer: new perspectives for targeted therapies [PDF]
, 2015 Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors.
Caruso, Davide +8 more
core +1 more source
T cell growth factor receptors. Quantitation, specificity, and biological relevance
Journal of Experimental Medicine, 1981 To examine directly the hypothesis that T cell growth factor (TCGF) interacts with target cells in a fashion similar to polypeptide hormones, the binding of radiolabeled TCGF to various cell populations was investigated.
R. Robb, A. Munck, KA Smith
semanticscholar +1 more source
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors
Cells, 2019 Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells.
Shuyan Dai +4 more
doaj +1 more source
Identification of kinases activated by multiple pro-angiogenic growth factors
Frontiers in Pharmacology, 2023 Antiangiogenic therapy began as an effort to inhibit VEGF signaling, which was thought to be the sole factor driving tumor angiogenesis. It has become clear that there are more pro-angiogenic growth factors that can substitute for VEGF during tumor ...
Scott Gruver +3 more
doaj +1 more source
Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin. [PDF]
, 2014 A long-standing issue in the field of signal transduction is to understand the cross-talk between receptor tyrosine kinases (RTKs) and heterotrimeric G proteins, two major and distinct signaling hubs that control eukaryotic cell behavior.
Abagyan, Ruben +8 more
core +1 more source
Activation of multiple growth factor signalling pathways is frequent in meningiomas [PDF]
, 2015 A minority of meningiomas are difficult to treat with surgery or radiotherapy, and chemotherapeutic alternatives are limited. This study aims to better understand pathways that are active in meningiomas, in order to direct future treatment strategies. We
Bassiri, K +5 more
core +2 more sources