Results 91 to 100 of about 89,612 (317)

Role and immunomodulatory profile of histamine receptors by H1 and H2 antagonists [PDF]

open access: yes, 2008
The present study was designed to delineate the immunomodulatory role of histamine receptors (H1- and H2-) on induction of antibody response to sheep red blood cells (SRBC), as well as the antibody generation profile, in rabbit system, systemically.
Mashiatullah Siddiqui   +3 more
core   +1 more source

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

open access: yes, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M   +183 more
core   +1 more source

Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology

open access: yesChemBioChem, EarlyView.
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda   +2 more
wiley   +1 more source

Recent Advances in Molecular Pharmacology of the Histamine Systems: Roles of C-terminal Tails of Histamine Receptors

open access: yesJournal of Pharmacological Sciences, 2006
.: G-protein-coupled receptors (GPCR) represent a large and diverse superfamily of integral membrane proteins to which histamine receptors belong. Increasing numbers of proteins have been identified to interact with the C-termini of GPCRs.
Kuramasu Atsuo   +3 more
doaj  

Effect of histamine on the electric activities of cerebellar Purkinje cell [PDF]

open access: yesarXiv, 1999
The effect of histamine (HA) on the electric activities of Purkinje cell (PC) is studied on the cerebellum slice. We find that: (1) HA's main effect on PC is excitative (72.9%); there are also a small amount of PC showing inhibitive (10.2%) or no (16.9%) response to HA.
arxiv  

Detection in Molecular Communications with Ligand Receptors under Molecular Interference [PDF]

open access: yesarXiv, 2020
Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to transfer information among bio-nano devices. In this paper, we focus on the detection problem for biological MC receivers employing ligand receptors to infer the transmitted messages encoded into the concentration of molecules, i.e., ligands.
arxiv  

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. [PDF]

open access: yes, 1983
Isolated dog mastocytoma cells sensitized with dog anti-ragweed IgE and challenged with ragweed antigen or incubated with ionophore A23187 or the carboxy-terminal dodecapeptide of platelet factor 4, PF4(59-70), release histamine and concurrently generate
Goetzl, EJ, Gold, WM, Phillips, MJ
core  

Distinct roles of NMB and GRP in itch transmission [PDF]

open access: yes, 2017
A key question in our understanding of itch coding mechanisms is whether itch is relayed by dedicated molecular and neuronal pathways. Previous studies suggested that gastrin-releasing peptide (GRP) is an itch-specific neurotransmitter. Neuromedin B (NMB)
Bardoni, Rita   +16 more
core   +3 more sources

From Allergy to Angina: A Unique Presentation of Kounis Syndrome

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Kounis syndrome (KS) is a rare condition characterized by acute coronary syndrome (ACS) triggered by an allergic reaction. This report presents a case of high‐risk ACS associated with a food allergy. A 53‐year‐old male with no prior medical history presented to the emergency department with itching, facial swelling, chest tightness, shortness ...
Momen Ali   +3 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi   +6 more
wiley   +1 more source

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