Results 171 to 180 of about 94,570 (290)

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

British Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich, Paul Schilf, Sripriya Murthy, Sina Gonther, Mareike Neumann, Christoph M. Hammers, Jasper N. Pruessmann, Christian D. Sadik   +7 more
wiley   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE-Mediated Anaphylaxis. [PDF]

Immunol Rev
Biswas R, Fried JM, Curotto de Lafaille MA.   +2 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Letter to the Editor in Response to "Efficacy and Safety of Histamine H3 Receptor Antagonist/Inverse Agonist Including Betahistine for Schizophrenia: A Systematic Review and Meta-Analysis" by Nishii et al. [PDF]

Neuropsychopharmacol Rep
Farhan M.
europepmc   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]

Geriatr Gerontol Int
Mogi M, Liu S, Suzuki Y, Shibata Y, Yamada S.   +4 more
europepmc   +1 more source

Expression profiles of itch markers during scabies infection in a porcine scabies model. [PDF]

PLoS Negl Trop Dis
Fernando DD, O'Grady J, Nguyen TH, Hartel G, Yosipovitch G, Fischer K.   +5 more
europepmc   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

Modulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects. [PDF]

Inflammopharmacology
Marcus WH, Ruby HA, Awwad AE, Mahrous MH, Abouelwafa E, Badawy MAS, El-Shiekh RA, Zaki ES, Mahmoud MA.   +8 more
europepmc   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

Microbial Diversity Affects the Cold Tolerance of Red Swamp Crayfish (Procambarus clarkii) by Regulating Histamine Metabolism. [PDF]

Microb Ecol
Hu H, Zhang Y, Liu Z, Han Y, Luo Y, Zhang C, Yu Y, Wang J, Li B, Su S.   +9 more
europepmc   +1 more source