Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
Effects of Haloperidol on Cardiac Histamine H<sub>2</sub> Receptors and β-Adrenoceptors in Isolated Mouse and Human Atrial Preparations. [PDF]
Schlicht JMA +4 more
europepmc +1 more source
Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers +2 more
wiley +1 more source
IgE Nonresponders in Basophil Activation Tests: A Narrative Review From Mechanistic Insights to Clinical Implications and Future Directions. [PDF]
Eberlein B, Biedermann T.
europepmc +1 more source
ABSTRACT Introduction Burning mouth syndrome (BMS) is occasionally accompanied by denture intolerance. Case Presentation An 80‐year‐old woman with complaints of residual and relapsed intraoral pain and denture intolerance due to BMS was improved by olanzapine without severe adverse events, and her eating ability was successfully restored.
Motoko Watanabe +7 more
wiley +1 more source
Repurposing the antihistamine cyproheptadine for osteoarthritis: nothing to sneeze at. [PDF]
Loeser RF, Coryell PR.
europepmc +1 more source
First successful protocol for desensitization to eptinezumab
Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard +8 more
wiley +1 more source
Unravelling the Intricate Link: Mast Cells and Estrogen-Induced Pain Sensitization in Endometriosis. [PDF]
Wang J, Mao X, Zhu L, Zhang X.
europepmc +1 more source
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for patients with advanced solid tumors. While low‐grade immune‐related adverse events (irAEs) are associated with prolonged survival, high‐grade irAEs have been associated with poorer survival. Cutaneous immune‐related adverse events (cirAEs) affect up to 20%
David O'Reilly +17 more
wiley +1 more source
Histamine regulates the activity and the expression of the Na<sup>+</sup>/H<sup>+</sup> exchanger (NHE)3 in human epithelial HK-2 cells. [PDF]
Gerbino C +6 more
europepmc +1 more source

