Results 11 to 20 of about 94,570 (290)

Network adaptation improves temporal representation of naturalistic stimuli in drosophila eye: II Mechanisms [PDF]

, 2009
Retinal networks must adapt constantly to best present the ever changing visual world to the brain. Here we test the hypothesis that adaptation is a result of different mechanisms at several synaptic connections within the network.
A Borst, A Kolodziejczyk, A Nikolaev, AD Straw, AL Fairhall, AL Fairhall, Anton Nikolaev, B Wark, BG Burton, BG Burton, BN Lundstrom, Cahir J. O'Kane, CE Shannon, DG Stavenga, DJ Field, DW Dong, E Schneidman, E Warrant, EL Mah, Ernest Greene, F Attneave, G Buchsbaum, G Schwartz, GG de Polavieja, GG de Polavieja, GG de Polavieja, Gonzalo G. de Polavieja, GW Davis, H Alle, H Barlow, H Clague, HG Krapp, I Sinakevitch, IA Meinertzhagen, IA Meinertzhagen, J Rister, J Tanaka, JD Armitage, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JH van Hateren, JJ Atick, JJ Atick, JL Puchalla, K Götz, K Kirschfeld, L Zheng, Lei Zheng, M Heisenberg, M Heisenberg, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Juusola, M Järvilehto, M Land, M Stemmler, M Weckstrom, Mikko Juusola, MV Srinivasan, N Brenner, N Uchida, O Faivre, O Sayeed, R Hummel, R Kern, R Linsker, R Segev, R Wolf, RC Hardie, RO Uusitalo, RR de Ruyter van Steveninck, RS Brinkworth, S Laughlin, S Tang, SA Baccus, SB Laughlin, SB Laughlin, SM Smirnakis, SN Fry, SN Fry, SR Shaw, ST Hong, T Gollisch, TM Cover, TO Sharpee, Trevor J. Wardill, V Wolfram, XJ Wang, Y Dan, Y Shu   +99 more
core   +11 more sources

Histamine 2 Receptor Agonism and Histamine 4 Receptor Antagonism Ameliorate Inflammation in a Model of Psoriasis

Acta Dermato-Venereologica, 2020
Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferative keratinocytes and immune cell infiltration into the skin, often accompanied by itch.
Kristine Rossbach, Katharina Wahle, Gustav Bruer, Ralph Brehm, Marion Langeheine, Kristina Rode, Katrin Schaper-Gerhardt, Ralf Gutzmer, Thomas Werfel, Manfred Kietzmann, Wolfgang Bäumer   +10 more
doaj   +1 more source

Votucalis, a Novel Centrally Sparing Histamine-Binding Protein, Attenuates Histaminergic Itch and Neuropathic Pain in Mice

Frontiers in Pharmacology, 2022
Votucalis is a biologically active protein in tick (R. appendiculatus) saliva, which specifically binds histamine with high affinity and, therefore, has the potential to inhibit the host’s immunological responses at the feeding site. We hypothesized that
Ibrahim Alrashdi, Ibrahim Alrashdi, Amal Alsubaiyel, Amal Alsubaiyel, Michele Chan, Michele Chan, Emma E. Battell, Abdel Ennaceur, Miles A. Nunn, Wayne Weston-Davies, Paul L. Chazot, Ilona Obara, Ilona Obara   +12 more
doaj   +1 more source

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

Archives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar, M Zendehdel, B Vazir, A Asghari   +3 more
doaj   +1 more source

Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery

Molecules, 2021
The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system ...
Pakhuri Mehta, Przemysław Miszta, Sławomir Filipek   +2 more
doaj   +1 more source

H3 histamine receptor-mediated activation of protein kinase calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo [PDF]

, 2009
Histamine regulates functions via four receptors (HRH1, HRH2, HRH3, and HRH4). The D-myo-inositol 1,4,5-trisphosphate (IP(3))/Ca(2+)/protein kinase C (PKC)/mitogen-activated protein kinase pathway regulates cholangiocarcinoma growth.
A. Vetuschi, F. Y. Meng, FRANCHITTO, Antonio, G. Alpini, G. Carpino, GAUDIO, EUGENIO, H. Francis, J. Venter, M. White, MANCINELLI, ROMINA, ONORI, PAOLO, R. Sferra, S. Demorrow, S. Kopriva   +13 more
core   +1 more source

Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor

Nature Communications, 2023
Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H4 receptor (H4R) is a potential therapeutic target for chronic inflammatory diseases such as asthma and atopic ...
Dohyun Im, Jun-ichi Kishikawa, Yuki Shiimura, Hiromi Hisano, Akane Ito, Yoko Fujita-Fujiharu, Yukihiko Sugita, Takeshi Noda, Takayuki Kato, Hidetsugu Asada, So Iwata   +10 more
doaj   +1 more source

Effects of histamine on human periodontal ligament fibroblasts under simulated orthodontic pressure.

PLoS ONE, 2020
As type-I-allergies show an increasing prevalence in the general populace, orthodontic patients may also be affected by histamine release during treatment.
Marcella Groeger, Gerrit Spanier, Michael Wolf, James Deschner, Peter Proff, Agnes Schröder, Christian Kirschneck   +6 more
doaj   +1 more source

Histamine and histamine receptors: Roles in major depressive disorder

Frontiers in Psychiatry, 2022
Although the incidence of major depressive disorder (MDD) is high and its social impact is great, we still know very little about the pathophysiology of depression.
Hong Qian, Hong Qian, Chang Shu, Ling Xiao, Gaohua Wang   +4 more
doaj   +1 more source

Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]

, 2017
Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S, Kim, Bo-Mi, Kim, Hae-Rim, Kim, Kyoung-Woon, Lee, Kyung-Ann, Lee, Sang-Heon   +5 more
core   +1 more source