Results 121 to 130 of about 18,066 (161)

Deciphering Histamine Pathway Networks in the Human Brain: A Multimodal Approach to Cognition and Psychiatric Disorders

Martins D, Veronese M, Wamelen Dv, Shan L, Howes O, Hampshire A, Turkheimer F, Williams SC.   +7 more
europepmc   +1 more source

Functional and phylogenetic analysis of placozoan GPCRs reveal the prebilaterian origin of monoaminergic signalling

Yañez-Guerra LA, Mayorova TD, Guan L, Jékely G, Wijnen H, Senatore A.   +5 more
europepmc   +1 more source

Inhibition of Histamine Release by Histamine controlled by H2 Receptor [PDF]

Nature, 1973
AGENTS which increase the intracellular level of adenosine 3′-5′-monophosphate (cyclic AMP) in human leukocyte preparations such as the catecholamines, methylxanthines and prostaglandins, inhibit the antigen induced, IgE antibody mediated release of histamine from human leukocytes (basophils)1–3.
Elizabeth Gillespie, Lawrence M. Lichtenstein   +1 more
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On the mechanism of histamine H2 receptor activation.

Molecular Pharmacology, 1987
The H2 receptor activation mechanism model proposed by Weinstein et al. [Mol. Pharmacol. 12:738-745 (1976)] has been considered for the set of H2 agonists. The energetics of the model proton transfer processes from a proton-donor site to the heterocycle ring of the agonist molecule and from this one to a proton acceptor site have been studied by using ...
F J, Luque, F, Illas, R, Pouplana
openaire   +2 more sources

Histamine H2-receptor antagonists

Baillière's Clinical Gastroenterology, 1988
The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine H2-Receptor Antagonists

Nursing Clinics of North America, 1991
In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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Histamine H2 receptors and cyclic AMP in brain

Life Sciences, 1974
Abstract The intravenous injection of histamine to 2–3 day old chicks resulted in a rapid and marked increase in the cyclic AMP content of the cerebral hemispheres that had been removed and frozen within 0.5s using a freeze-blowing technique. This response was not antagonized by pretreatment of the chicks with the histamine H1-receptor antagonists ...
Brenda M. Smith, Stephan R. Nahorski, Keith J. Rogers   +2 more
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Histamine H2-receptors on single central neurones

Nature, 1975
THE detection of histamine H2-receptor antagonists1,2 has provided fresh impetus to the investigation of central effects of histamine3–7 and its possible role as a neurotransmitter3,8–10. In the hypothalamus of rat and cat microelectrophoretically applied histamine excites a large number of cells.
Helmut L. Haas, U M Bucher
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Histamine H2 Receptor-Antagonists

JAMA: The Journal of the American Medical Association, 1976
Histamine H 2 receptor-antagonists—burimamide, metiamide, cimetidine—are currently arousing much anticipatory excitement. The relatively recent concept that there is more than one receptor for histamine is based on the observation that pyrilamine (mepyramine) and other, older antihistamines have no effect on histamine-mediated secretion of gastric acid
openaire   +3 more sources