Results 31 to 40 of about 42,332 (197)

Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor. [PDF]

open access: yesPLoS ONE, 2012
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases.
Ying Shi   +9 more
doaj   +1 more source

Histamine, histamine receptors, and neuropathic pain relief

open access: yesBritish Journal of Pharmacology, 2019
Histamine, acting via distinct histamine H1, H2, H3, and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement of H3 ...
I. Obara   +3 more
semanticscholar   +1 more source

Histamine H2-receptor antagonists for urticaria

open access: yesCochrane Database of Systematic Reviews, 2012
Urticaria is a common skin disease characterised by itching weals or hives, which can occur almost anywhere on the body. There are a number of different subtypes and a range of available treatment options. There is lack of agreement on the efficacy of H2-receptor antagonists used in the treatment of urticaria.To assess the safety and effectiveness of ...
Fedorowicz, Z.   +2 more
openaire   +4 more sources

Predictors of Response to Oral Medications and Low-Histamine Diet in Patients with Chronic Urticaria

open access: yesJournal of Immunology Research, 2022
Background. Chronic urticaria (CU) is comprised of diverse phenotypes, and thus, a shift towards a precision medical approach is warranted in its management. Methods. This study enrolled 78 patients with CU.
Hui-Ling Chiang   +4 more
doaj   +1 more source

Mast Cells May Differentially Regulate Growth of Lymphoid Neoplasms by Opposite Modulation of Histamine Receptors

open access: yesFrontiers in Oncology, 2019
Cancer microenvironment is complex and consists of various immune cells. There is evidence for mast cell (MC) infiltration of tumors, but their role thereof is poorly understood.
Sandeep Paudel   +2 more
doaj   +1 more source

Histamine H2 Receptor Trafficking: Role of Arrestin, Dynamin, and Clathrin in Histamine H2 Receptor Internalization

open access: yesMolecular Pharmacology, 2008
Agonist-induced internalization of G protein-coupled receptors (GPCRs) has been implicated in receptor desensitization, resensitization, and down-regulation. In the present study, we sought to establish whether the histamine H2 receptor (H2r) agonist amthamine, besides promoting receptor desensitization, induced H2r internalization.
Fernandez, Natalia Cristina   +4 more
openaire   +3 more sources

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source

Identification of histaminic (H1-type) receptors in small intestine of broilers by application of histamine and some of its agonists and antagonists [PDF]

open access: yesVeterinarski Glasnik, 2010
Histamine is a biologically active amine (biogenic amine) that has a broad spectra of physiologic and pathologic reactions in the organism. Its effects are shown through 4 types of specific receptors (H1, H2, H3 and H4).
Mujezinović Indira   +3 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Histamine induced high mobility group box-1 release from vascular endothelial cells through H1 receptor

open access: yesFrontiers in Immunology, 2022
BackgroundSystemic allergic reaction is characterized by vasodilation and vascular leakage, which causes a rapid, precipitous and sustained decrease in arterial blood pressure with a concomitant decrease of cardiac output.
Shangze Gao   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy