Results 71 to 80 of about 42,332 (197)

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

Львівський клінічний вісник, 2019
Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the ...
Pliatsko M.
doaj   +1 more source

Histamine H2 Receptors in Nasal Mucosa.

Practica Oto-Rhino-Laryngologica, 1994
Nasal mucous membrane is a pathogenic site of Type I allergy (nasal allergy), and a number of studies have suggested the involvement of histamine H1 receptors in this region.Histamine H2 receptors, which are considered to suppress the activity of many immunity-related cells have, however been studied insufficiently.In this study, the number of ...
Shigehiko SATOH, Hitoshi SHIMADA, Kohtaro BABA   +2 more
openaire   +2 more sources

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

Stem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao, Youchao Chen, Li Cheng, Lishi Fan, Han Chen, Yushan Wan, Yi You, Yanrong Zheng, Lei Jiang, Zhong Chen, Xiangnan Zhang, Weiwei Hu   +11 more
doaj   +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

Mediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj   +1 more source

Antinociceptive mechanisms of Bunium persicum essential oil in the mouse writhing test: role of opioidergic and histaminergic systems

Veterinární Medicína, 2015
Bunium persicum (Boiss.) is an economically important medicinal plant growing wildly in arid regions in Iran. The fruit of B. persicum is widely used in traditional Iranian medicine to control colic pain and dysmenorrhoea.
M. Zendehdel, Z. Torabi, S. Hassanpour
doaj   +1 more source

Histamine Regulates Molecular Clock Oscillations in Human Retinal Pigment Epithelial Cells via H1 Receptors

Frontiers in Endocrinology, 2018
Vertebrate eyes are known to contain circadian clocks, but their regulatory mechanisms remain largely unknown. To address this, we used a cell line from human retinal pigment epithelium (hRPE-YC) with stable coexpression of reporters for molecular clock ...
Eri Morioka, Yuzuki Kanda, Hayato Koizumi, Tsubasa Miyamoto, Masayuki Ikeda   +4 more
doaj   +1 more source

The Impact of H1–H4 Receptor Antagonists on the Levels of Selected Oxidative Stress Markers in Liver and Muscle Tissue in an Animal Model of Colitis

Pharmaceuticals
Background/Objectives: The global prevalence and incidence of inflammatory bowel diseases have risen in the past two decades. Among them, Crohn’s disease and ulcerative colitis are still challenging to treat due to vascular and proliferative alterations.
Bartosz Bogielski, Katarzyna Michalczyk, Wojciech Gębski, Katarzyna Rozpędek, Elżbieta Szulińska, Bartosz Tempka, Aleksandra Zorychta, Elżbieta Chełmecka, Ewa Kaczmar, Piotr Głodek, Jakub John, Kamil Nikiel, Bronisława Skrzep-Poloczek, Jerzy Jochem, Katarzyna Kieć-Kononowicz, Dorota Łażewska, Dominika Stygar   +16 more
doaj   +1 more source

Mechanistic Insights into the Interaction Between Kinin Receptors and Histamine H2 Receptor Pathways in Oxidative Stress

Receptors
Reactive oxygen species (ROS) encompass various molecular oxygen derivatives naturally produced during aerobic metabolism, including superoxide anions, hydrogen peroxide, and hydroxyl radicals.
Marcos Fernandes Gregnani, Leonardo Martins, Wieslawa Agnieszka Fogel   +2 more
doaj   +1 more source

Abstracts

Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley   +1 more source

Antihistamines: Beyond just allergy treatment

Vietnam Journal of Science, Technology and Engineering
Histamine and its receptors (H1R-H4R) are involved in several significant physiological processes and pathogenic conditions. Antihistamines, widely recognised as drugs for treating allergies, belong to the H1 antihistamine group, which targets H1R on ...
Hue T. H. Bui, Xuan-Hung Nguyen
doaj