Results 61 to 70 of about 784,733 (223)
Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]
, 2009 Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bartness, Timothy J. +7 more
core +1 more source
Enhanced histamine H2 excitation of striatal cholinergic interneurons in l-DOPA-induced dyskinesia
Neurobiology of Disease, 2015 Levodopa is the most effective therapy for the motor deficits of Parkinson's disease (PD), but long term treatment leads to the development of l-DOPA-induced dyskinesia (LID).
Sean Austin O. Lim +7 more
doaj +1 more source
Veterinary Dermatology, EarlyView.Background: Currently used methods for the interpretation of intradermal allergen test results either ignore the erythema of the wheals (objective method) or evaluate it subjectively (subjective method, and global wheal score [GWS]). Objectives: To compare the efficacy of GWSs in differentiating between wheals induced by intradermal injection of a ...
Ana Petak +5 more
wiley +1 more source
Permeability of rat IgE across rat aortic endothelial cell is enhanced by histamine
Allergology International, 2001 Background: It is a well-known fact that IgE is a key substance that induces an allergic reaction in extravascular tissue. However, it remains to be elucidated how IgE in the circulating blood transfers to the site of the allergic reaction in the ...
Kazuhiko Hanashiro +4 more
doaj +1 more source
DEN Open, Volume 7, Issue 1, April 2027.ABSTRACT Background and Aim: Obscure gastrointestinal bleeding (OGIB) is defined as bleeding of unknown origin after comprehensive upper, lower, and small‐bowel evaluations. However, the incidence and predictors of rebleeding after negative comprehensive gastrointestinal evaluation remain unclear.
Sachiyo Onishi +8 more
wiley +1 more source
Histamine H3 Receptor Heterogeneity in the Central Nervous System in Aging and Dementia. [PDF]
, 2011 The histamine H3R is a classic G-protein coupled receptor and is a potential therapeutic target for a number of central nervous system pathologies. Major pharmacological heterogeneity between and within species has hindered the clinical development of ...
LETHBRIDGE, NATASHA,LOUSIE
core
British Journal of Pharmacology, Volume 183, Issue 20, Page 6007-6027, October 2026.Background and Purpose G protein‐coupled receptors (GPCRs) are integral membrane proteins that mediate physiological processes by enabling cells to detect and respond to diverse stimuli. Although many subfamily‐specific functional hotspots have been described, the family‐wide determinants of common and subfamily‐specific functions remain incomplete ...
Berkay Selçuk +3 more
wiley +1 more source
Molecular cloning of the human histamine H2 receptor [PDF]
Biochemical and Biophysical Research Communications, 1991 We utilized the technique of polymerase chain reaction with oligonucleotide primers based upon the nucleotide sequence of the canine H2 histamine receptor gene which we recently isolated to clone its human homologue. Transfection of a construct of this gene in Colo-320 DM cells led to the expression of a receptor that bound to [methyl-3H] tiotidine and
Gantz, Ira +6 more
openaire +3 more sources
Effects of administration of histamine and its H1, H2, and H3 receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s): The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on ...
Esmaeal Tamaddonfard +1 more
doaj
FEBS Open Bio, Volume 16, Issue 9, Page 1825-1839, September 2026.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source