Results 121 to 130 of about 37,159 (265)

The Utility of Intranasal Corticosteroids in Association With Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: A Real‐Life Multicenter Study by a Tuscany Group

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando, Giuseppe Licci, Marella Reale, Veronica Seccia, Alessia Giorli, Paolo Iannicelli, Dario Zaccari, Valentina Rossi, Jacopo Cambi, Stefano Berrettini, Marco Mandalà, Gianluca Leopardi, Antonio Sarno, Luca Muscatello, Simone Bocuzzi, Franco Trabalzini, Giandomenico Maggiore, Oreste Gallo   +17 more
wiley   +1 more source

The interplay between probiotics and mast cells in gut inflammation: a mini-review. [PDF]

Front Cell Infect Microbiol
Herrera-Saldivar MF, Hernandez-Bautista NC, Quiroga-Garza JM, Vazquez-Guillen JM, Chacon-Salinas R, Rojas-Contreras M, Vazquez-Juarez R, Resendez-Perez D, Tamez-Guerra RS, Rodriguez-Padilla C.   +9 more
europepmc   +1 more source

Distinct Nasal Microbiome Profiles and Prediction Model for Allergic Rhinitis, Nonallergic Rhinitis, and Healthy Children

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
The alpha and beta diversity of the nasal microbiome differed among children with allergic rhinitis (AR), nonallergic rhinitis (NAR), and healthy controls (HCs). Compared to HC, AR had more Escherichia‐Shigella, Negativicoccus, and Campylobacter, while NAR had more Dolosigranulum and fewer Enterobacteriaceae.
Kantima Kanchanapoomi, Iyarit Thaipisuttikul, Perapon Nitayanon, Witchaya Srisuwatchari, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk   +6 more
wiley   +1 more source

Immunological Basis of Chronic Spontaneous Urticaria: Immunoglobulin E and Beyond. [PDF]

Yonsei Med J
Rhyou HI, Nam YH, Park JW, Park HS.
europepmc   +1 more source

Enhanced Early Detection of Allergic Rhinitis: A Prospective Study on a Symptom‐Based Predictive Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Allergic rhinitis (AR) and non‐allergic rhinitis (NAR) share overlapping symptoms but differ in pathophysiology and treatment. Current AR diagnosis relies on skin prick testing (SPT) and serum IgE quantification, both of which are complex.
Ke‐Zhang Zhu, Chao He, Si‐Zhe Zhu, Zheng Liu, Ming Zeng   +4 more
wiley   +1 more source

Adjuvant Strategies to Improve the Efficacy of Allergen Immunotherapy. [PDF]

J Inflamm Res
Tabynov K, Tabynov K, Petrovsky N.
europepmc   +1 more source

Peanut Component‐Specific IgE and IgG4 Are Modulated by Sublingual Immunotherapy and Are Associated With Remission in 1–4‐Year‐Old Children

Allergy, EarlyView.
This study presents a post hoc analysis of longitudinal changes in peanut component‐specific IgE and IgG4 in children aged 1–4 years undergoing peanut SLIT, aiming to uncover immune mechanisms and potential biomarkers of remission. Peanut SLIT reduced IgE and increased IgG4 responses to Ara h 1, Ara h 2, Ara h 3, and Ara h 6.
Neel Singh, Janelle Kesselring, Jess Humphrey, Lauren Herlihy, A. Wesley Burks, Johanna Smeekens, Corinne Keet, J. Andrew Bird, Edwin H. Kim, Michael Kulis   +9 more
wiley   +1 more source

The AhR-TLR4 axis in non-IgE-mediated Cow's milk allergy: a systematic review with integrated multi-omics corroboration. [PDF]

Front Allergy
Kong W, Wu B, Huang Y, Liu H, Huang C.
europepmc   +1 more source

“Super‐Responders” to Dupilumab Treatment in Patients With Primary Diffuse Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk, J. J. Otten, H. B. E. Elzinga, R. J. L. van der Lans, G. F. J. P. Adriaensen, L. B. L. Benoist, D. R. Hoven, W. J. Fokkens, S. Reitsma, PolyREG Consortium, A.B. Rinia, I. Krebbers, I.J. Kleiss, M. E. Cornet   +13 more
wiley   +1 more source

Cross-Reactivity and Cross-Intolerance Among Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Clinical Patterns, COX-1-Mediated Mechanisms, and Implications for COX-2 Inhibitors and Paracetamol. [PDF]

Int J Mol Sci
Andryszkiewicz W, Lippik M, Makieła M, Modrzyk B, Gomułka K.   +4 more
europepmc   +1 more source