Results 141 to 150 of about 637,770 (292)
Liposomal Delivery Systems for Allergen-Specific Immunotherapy: From Molecular Design to Clinical Application. [PDF]
Melnikova DN +3 more
europepmc +1 more source
The polysaccharide Pullulan improves the initial steps of allergen‐specific immunotherapy in dogs
Abstract Background Allergen‐specific immunotherapy (AIT) is the only aetiological treatment for canine atopic dermatitis (CAD). Pullulan, a polysaccharide with immunomodulatory properties, may enhance AIT outcomes when combined with allergens such as recombinant Dermatophagoides farinae 2 (Der f 2).
Franco Martini +3 more
wiley +1 more source
Pathophysiological Drivers of Mast Cell Activation Syndrome and Implications for Treatment. [PDF]
Collins S +3 more
europepmc +1 more source
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
FcεRII (CD23) in dermatological disorders: structure, function, and clinical implications. [PDF]
Zdanowska N +4 more
europepmc +1 more source
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah +19 more
wiley +1 more source
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu +6 more
wiley +1 more source
Autosomal recessive OSMRβ deficiency: Connecting OSM and/or IL-31 with atopy. [PDF]
Puel A, Casanova JL, Béziat V.
europepmc +1 more source
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando +17 more
wiley +1 more source

