The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti +16 more
wiley +1 more source
Antibody-Dependent Enhancement in Flavivirus Infections: From Fc Receptor Signaling to Vaccine and Therapeutic Design. [PDF]
Li Y, Wu Z, Cha Y, Pang W, Sun L.
europepmc +1 more source
ABSTRACT Physical urticaria is a subtype of chronic inducible urticaria characterized by wheals and/or angioedema triggered by physical stimuli. We report a refractory case of combined localized heat urticaria, delayed solar urticaria, and symptomatic dermographism in a 16‐year‐old girl.
Shuta Yoshitani +2 more
wiley +1 more source
Bioactive compound ginkgolide B alleviates food allergy by regulating mTOR signaling pathway. [PDF]
Zhou R +5 more
europepmc +1 more source
Three molecular profiles identified among Art v 1/Amb a 4‐sensitized patients: Art v 1 monosensitization, Amb a 4 monosensitization, and dual sensitization to both allergens. Art v 1 monosensitization was predominantly associated with allergic rhinitis, reflecting a classical airborne allergy pattern.
Enrico Scala +20 more
wiley +1 more source
Targeting immune dysregulation in chronic spontaneous urticaria: beyond antihistamines. [PDF]
Ye YM.
europepmc +1 more source
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza +16 more
wiley +1 more source
The language of the immune system: Part 1: Cytokine conversations and conversationalists. [PDF]
Rosenthal KS.
europepmc +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Lysophosphatidic Acid Receptor 5 (LPA<sub>5</sub>) Antagonist AS2717638 Attenuates Allergic Asthma by Reducing Mast Cell Degranulation and Th2 Inflammation in Mice. [PDF]
Jeong SW, Im DS.
europepmc +1 more source

