Results 71 to 80 of about 75,053 (306)

Vascular endothelial growth factor (VEGF) serological and lacrimal signaling in patients affected by vernal keratoconjunctivitis (VKC) [PDF]

open access: yes, 2018
Background. Vernal keratoconjunctivitis (VKC) is a rare inflammatory disease involving the ocular surface, with seasonally exacerbated symptoms. Both type-1 and type-4 hypersensitivity reactions play a role in the development of VKC. Purpose.
Aventaggiato, Michele   +5 more
core   +1 more source

Work‐Related Asthma From Exposure to Cardboard and Paper Products

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background We assess the contribution of cardboard dust exposure to the development of work‐related asthma (WRA). Prior studies on paper‐dust‐related breathing problems have focused on exposures in the paper milling and pulp industries. There have been no reports of asthma linked to workplace exposure to cardboard dust.
Mason E. Glanville   +2 more
wiley   +1 more source

The pharmacological mechanisms of omalizumab in patients with very high IgE levels—Clues from studies on atopic dermatitis

open access: yesDermatologica Sinica, 2012
Seventeen case series investigating the effects of omalizumab on patients with atopic dermatitis included patients whose pretreatment serum IgE was above 700 IU/ml, the upper inclusion limit specified in the product label.
Tse Wen Chang, Jiun-Bo Chen, Chia-Yu Chu
doaj   +1 more source

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. [PDF]

open access: yes, 1983
Isolated dog mastocytoma cells sensitized with dog anti-ragweed IgE and challenged with ragweed antigen or incubated with ionophore A23187 or the carboxy-terminal dodecapeptide of platelet factor 4, PF4(59-70), release histamine and concurrently generate
Goetzl, EJ, Gold, WM, Phillips, MJ
core  

The clinical meaning of histamine skin reactivity [PDF]

open access: yes, 2015
The definition of the “atopic state”, i.e. subjects presenting at least one skin wheal with a minimum diameter of 3 mm induced by an allergen skin-prick test (ASPT), is based on the assumption that wheal size depends entirely on the amount of histamine
BARRETO, Mario, RONCHETTI, ROBERTO
core   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu   +6 more
wiley   +1 more source

NOSOTROPIC SUBSTANTIATION OF ANTI IgE ANIBODY THERAPY

open access: yesПедиатрическая фармакология, 2008
This article studies the specifics of allergic diseases pathogenesis. Such common allergic diseases as bronchial asthma, allergic rhinitis and atopic dermatitis are conditioned by processes based on increase of immunoglobulin e synthesis.
Yu.G. Levina
doaj   +2 more sources

Peripheral IgE Repertoires of Healthy Donors Carry Moderate Mutation Loads and Do Not Overlap With Other Isotypes

open access: yesFrontiers in Immunology, 2019
IgE-mediated allergic disease represents an increasing health problem. Although numerous studies have investigated IgE sequences in allergic patients, little information is available on the healthy IgE repertoire.
Marvyn T. Koning   +6 more
doaj   +1 more source

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park   +9 more
wiley   +1 more source

Structural Aspects of the Allergen-Antibody Interaction

open access: yesFrontiers in Immunology, 2020
The development of allergic disease involves the production of IgE antibodies upon allergen exposure in a process called sensitization. IgE binds to receptors on the surface of mast cells and basophils, and subsequent allergen exposure leads to cross ...
Anna Pomés   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy