Results 211 to 220 of about 296,832 (268)
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Macrophage receptors for IgG aggregates
Experimental Cell Research, 1970Abstract Uptake of aggregated heterologous IgG by mouse peritoneal cells in vitro was found to proceed in the absence of humoral complement, but to depend upon the C′-activating properties of the aggregates. This finding, together with results obtained in inhibition experiments using antimacrophage and anti-beta-1C sera, may indicate the existence of
M W, Hess, E F, Lüscher
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Annals of Hematology, 1998
IgG immune complexes are of central importance in the humoral immune system and strongly implicated in the pathogenesis of hematologic and rheumatic autoimmune disorders. Cross-linking of receptors for the Fc domain of IgG antibodies (FcgammaRs) triggers a wide variety of effector functions including phagocytosis, antibody-dependent cellular ...
J E, Gessner +3 more
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IgG immune complexes are of central importance in the humoral immune system and strongly implicated in the pathogenesis of hematologic and rheumatic autoimmune disorders. Cross-linking of receptors for the Fc domain of IgG antibodies (FcgammaRs) triggers a wide variety of effector functions including phagocytosis, antibody-dependent cellular ...
J E, Gessner +3 more
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Heterogeneity of Human IgG Fc Receptors
ImmunoMethods, 1994The complex family of human IgG Fc receptors show a wide cellular distribution and a strong functional heterogeneity. To date, eight different genes that are transcribed into at least 12 different mRNAs have been recognized. Although corresponding products have been identified for only some of the transcripts, in vivo at least six different Fc gamma R ...
P J, Capel +3 more
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IgG receptors on the mast cell
Agents and Actions, 1981Antisera to the IgG subclasses, 1, 2a, 2b, and 2c, induced histamine release from mast cells obtained from the peritoneal washings of Lister hooded rats. The maximum responses obtained with anti-IgG1 and anti-IgG2a were as great as that for anti-IgE (more than 60% histamine release). Cells from unresponsive Wistar rats which did not secrete appreciable
I, Moodley, J L, Mongar
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IgG Fc‐binding receptors on spermatozoa
European Journal of Immunology, 1980AbstractThe ability of human and mouse spermatozoa to bind immunoglobulin to their surfaces was investigated by a binding assay using radioiodinated Ig. The results suggest that spermatozoa of both human and mouse origin possess Fc receptors, i.e. they have the ability to bind Fcγ region.
K K, Sethi, H, Brandis
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The Unique Inhibitory IgG Receptor--FcγRIIb
Protein & Peptide Letters, 2018FcγRIIb is the only inhibitory IgG receptor, which is divided into three subtypes of FcγRIIb1, FcγRIIb2 and FcγRIIb3. It is mainly responsible for the immune balance in vivo by cross-linking with the activated receptor to intracellular transduction inhibitory signals, and it plays an important biological role in the negative regulation of innate ...
Zhenzhen, Xu +6 more
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Clinical Immunology and Immunopathology, 1989
Considerable recent progress has been made in our understanding of how IgG immune complexes interact with plasma membrane Fc receptors (FcR) to mediate a diversity of biological responses in man. These responses include endocytosis of antibody complexes; stimulation of the secretion of various inflammatory mediators such as enzymes, oxygen products ...
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Considerable recent progress has been made in our understanding of how IgG immune complexes interact with plasma membrane Fc receptors (FcR) to mediate a diversity of biological responses in man. These responses include endocytosis of antibody complexes; stimulation of the secretion of various inflammatory mediators such as enzymes, oxygen products ...
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International Reviews of Immunology, 1989
Human lymphocytes bear at least three different classes of Fc gamma R, which are different in cellular distribution, structure, and function. This review deals with recent advances in understanding the complexity of huFc gamma R. In particular, studies demonstrating the presence of alternate phosphatidyl inositol glycan-anchored and transmembrane ...
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Human lymphocytes bear at least three different classes of Fc gamma R, which are different in cellular distribution, structure, and function. This review deals with recent advances in understanding the complexity of huFc gamma R. In particular, studies demonstrating the presence of alternate phosphatidyl inositol glycan-anchored and transmembrane ...
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Inflammation in autoimmunity: receptors for IgG revisited
Trends in Immunology, 2001During the past decade, our knowledge of Fc receptor interactions in inflammation has increased dramatically owing to the availability of single and multiple Fc-receptor-deficient mice. The deletion of activating Fc gamma receptors protects against inflammation in models of immune-complex-mediated diseases, whereas the deletion of inhibitory Fc gamma ...
H M, Dijstelbloem +2 more
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IgG‐Fc‐Receptors of Group C Streptococci
Journal of Veterinary Medicine, Series B, 1987SummaryNon‐immune binding of human IgG to streptococci of serological group C could be readily detected on nitrocellulose membranes by direct cultivation of the streptococci or microfiltration of their culture supernatants. Further, quantitative determinations of Fc‐receptor activities with 125I‐IgG preparations revealed, that all 11 cultures of S ...
C, Frede, C, Lämmler, H, Blobel
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