Results 221 to 230 of about 296,832 (268)

IgG receptor polymorphisms: risk factors for disease

Immunogenetics, 1998
Two groups of receptors for immunoglobulin G (FcgammaR) can be distinguished. Endothelial cells and placental syncytiotrophoblasts express an MHC class I-like FcgammaR important for regulation of IgG half-life and IgG transport, respectively. FcgammaR expressed on leukocytes constitute a heterogeneous family of membrane bound and soluble proteins.
W, van der Pol, J G, van de Winkel
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IgG receptors on foetal chick yolk sac

Journal of Cell Science, 1978
ABSTRACT In the chicken, maternal IgG is deposited in the oocyte yolk and subsequently transported intact by the foetal chick yolk sac into the chick circulation. Such transport appears to require a specific membrane-localized IgG receptor.
C D, Linden, T F, Roth
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IgG Fc Receptors: Evolutionary Considerations

2019
Immunoglobulins (Ig), a critical component of the adaptive immune system, are present in all jawed vertebrates and through sophisticated diversification mechanisms are able to recognize antigens of almost infinite diversity. During mammalian evolution, IgG has emerged as the predominant Ig isotype that is elicited upon antigenic challenge, representing
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IgG Receptors in Alzheimer’s Disease

Science Signaling, 2013
An interaction between the IgG receptor FcγRIIb and β-amyloid contributes to the neuropathology of Alzheimer’s disease.
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Phagocyte Fc receptors for IgG

1998
This chapter focuses on the Fc receptors for IgG (FcγR) on phagocytic cells, e.g. polymorphonuclear neutrophils (PMNs), monocytes and macrophages. Eosinophils and basophils/mast cells which also have phagocytic properties are not discussed. PMNs and monocytes circulate in the bloodstream and are derived from pluripotent haematopoietic stem cells in the
S. E. Mckenzie, Z. K. Indik, A. D. Schreiber   +2 more
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Characterization of human IgG Fc receptors.

The Journal of Immunology, 1985
Abstract A murine monoclonal antibody, KuFc79, has been developed that reacts with human IgG Fc receptors on monocytes, B lymphocytes, and granulocytes. The specificity of KuFc79 for Fc receptors was demonstrated by the ability of Fab fragments to block Fc-mediated phagocytosis by monocytes.
M, Vaughn, M, Taylor, T, Mohanakumar
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Human Lymphocytes with Receptors for IgG

International Archives of Allergy and Immunology, 1974
Human lymphocytes with receptors for IgG (EA-RFC) were detected in peripheral blood by their ability to form rosettes with human erythrocytes sensitized with human (Ripley anti-CD) or rabbit IgG. EA-RFC were shown to be different from T-lymphocytes forming rosettes with sheep erythrocytes (E-RFC), both by direct studies of mixed rosette suspensions and
S.S. Frøland, F. Wisløff, E. Michaelsen   +2 more
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Molecular Mimicries between Human IgG, IgM Rheumatoid Factor and Streptococcal IgG Fc Receptors

Scandinavian Journal of Rheumatology, 1988
A monoclonal IgM rheumatoid factor (RF) from a patient with mixed essential cryoglobulinaemia was found to bind to type M15 group A streptococci with high affinity. The reaction was exerted via the antibody combining sites since it was inhibited by F(ab')2 fragments of anti-idiotypic (Id) antibodies but not by F(ab')2 of anti-IgMFc or normal rabbit IgG.
A K, Schröder, P, Christensen
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Molecular Interactions between Human IgG, IgM Rheumatoid Factor and Streptococcal IgG Fc Receptors

International Archives of Allergy and Immunology, 1988
Group A streptococci type M15 were previously shown to bind both human IgG via the Fc component and a purified monoclonal IgM kappa rheumatoid factor (IgM RF). Using ¹²⁵I-labelled IgG and ¹²⁵I-la-belled IgM RF, the present study gave association constants of 2.2 × 10⁷ and 2.9 × 10< ...
A K, Schröder, A E, Gharavi, P, Christensen   +2 more
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Cytotoxicity mediated by human Fc receptors for IgG

Immunology Today, 1989
The Fc receptors for IgG(Fc gamma R) play a major role in the removal of antibody-coated infectious agents and may be important molecules for triggering cytotoxicity of tumor cells; they may also serve as an entry for infection of Fc gamma R-bearing cells by viral (including HIV and Dengue), and perhaps other infectious agents.
M W, Fanger, L, Shen, R F, Graziano, P M, Guyre   +3 more
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