Results 101 to 110 of about 479,777 (310)
Viruses, 2019 Multisystemic inflammation in pigs affected by porcine circovirus type 2 (PCV2) indicates the disordered expression of inflammatory cytokines. However, the PCV2-induced expression profile of inflammation cytokines and its regulating mechanism remain ...
Shunli Yang +7 more
doaj +1 more source
Post-transcriptional inhibition of the interleukin-1 binding protein B15R of Vaccinia virus after coexpression of the related T1 protein [PDF]
, 1995 The interleukin-1 binding B15R protein of Vaccinia virus and murine T1 are related extracellular glycoproteins with similarity to the extracellular domain of interleukin-1 receptors.
Danescu, Joana, Werenskiold, Anne Katrin
core +1 more source
Diverse Treatment Goals in Psoriatic Arthritis: Insights From Participants in the PARC Cohort
Arthritis Care &Research, EarlyView.Objective The aim of this study was to examine patient‐reported treatment goals among individuals with psoriatic arthritis. Methods Participants in the Psoriatic Arthritis Research Consortium completed standardized assessments, including patient‐reported outcome (PROs) instruments, between 2017 and 2020.
Astia Allenzara +8 more
wiley +1 more source
Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
, 2008 Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Ivan Mikula Jr. +6 more
core +1 more source
Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist [PDF]
Proceedings of the Nutrition Society, 1994 Edward M. Copeland +3 more
openaire +2 more sources
Metabolic Consequences of Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry +2 more
wiley +1 more source
IL-38: A New Player in Inflammatory Autoimmune Disorders
Biomolecules, 2019 Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36
Lihui Xie +5 more
doaj +1 more source
Constitutive expression of high affinity interleukin 2 receptors on human CD16-natural killer cells in vivo. [PDF]
, 1990 The majority of human NK cells express low affinity IgG Fc receptors (CD16+), whereas a minor subset of NK cells lack Fc receptor expression (CD16-). In contrast to CD16+ NK cells that express only p75 IL-2 receptors, CD16- NK cells constitutively co ...
Lanier, LL, Nagler, A, Phillips, JH
core
Arthritis Care &Research, EarlyView.Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder +5 more
wiley +1 more source
Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis [PDF]
Annals of the Rheumatic Diseases, 2000 Chronic arthritis is characterised by chronic joint inflammation and concurrent joint erosion and destruction. The inflammatory cytokine interleukin 1 (IL1) has been shown to be a key mediator in the autoimmune disease rheumatoid arthritis (RA). Interleukin 1 mediates bone resorption and cartilage destruction, but may not play as dominant a part in ...
openaire +3 more sources