Results 81 to 90 of about 30,474,151 (303)
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist : a Mendelian randomisation analysis [PDF]
, 2015 Funded by: UK Medical Research Council, British Heart Foundation, UK National Institute for Health Research, National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council, and European Commission Framework ...D. F. Easton (7608179), Howson, Joanna M M, Singleton, A, E. Harshfield (7646096), Sanna, Serena, Hall, A.S. (Alistair), Bown, Matthew J, Stefánsson, K., Staley, James R, Dunlop, M., Rasmussen-Torvik, L.J. (Laura), B. G. Nordestgaard (7605362), Langefeld, C.D. (Carl), Grande, P, Sanna, S., Smith, AV, G. F. Mitchell (7646183), Kooner, J.S. (Jaspal S.), Felix, J.F., Gudnasson, Vilmundur, Carrell, D. S., McCarty, Catherine A., D. Crossman (7646276), Hakonarson, Hakon, Franco, O.H., Stefansson, K, Nelson, C.P. (Christopher P.), Walston, J. (Jeremy), Eisen, T. (Timothy), Hofman, A., Crosslin, D.R., Assimes, T, D. T. Bishop (7646264), de Bakker, Paul I. W., Gorski, M. (Mathias), Malinowski, J. (Jennifer), G. Tromp (7646132), Li, Yong, Goldschmidt, Hartmut, Y. Wang (473169), M. Sudman (7646219), Ferreira, MA, Crawford, DC, Weidinger, S., T. Kessler (7646111), Nielsen, SF, E. Di Angelantonio (7611773), McCarty, C.A. (Catherine A.), O. Gottesman (7646165), März, Winfried, Gorski, Mathias, Hall, AS, J. R. Staley (7646090), Iles, M.M., Hayward, NK, Hopewell, J. C., Peissig, P.L., Brown, Matthew J., Bevan, S, P. Willeit (7605167), Nordestgaard, B.G., L. A. Lange (7646105), Kessler, Thorsten, Delgado, G.E., Law, M. H., Delgado, G., Franceschini, N. (Nora), Nalls, M.A., Zhang, W., Hopewell, Jemma C., Harshfield, E, Delgado, G. E., Franco, O. H., N. J. Timpson (7608851), Tracy, Russell, Franceschini, N, Delgado, GE, H. Baurecht (7646204), M. de Andrade (7646150), Butterworth, Adam S, Bown, M.J., Polychronakos, C. (Constantin), Kooner, J.S., Schunkert, H, A. F. Baas (7646126), Li, Yunlei, Nalls, M.A. (Michael), N. J. Samani (7591811), Peissig, Peggy L., Bown, MJ, de Andrade, Mariza, Wareham, N.J., Nelson, CP, Scott, Robert A., Li, Y., Nejentsev, S., Allan, JM, M. Gorski (7626956), Evans, D.M. (David M.), Van 'T Hof, F.N.G. (Femke), A. A. S. Majumder (7646297), Erdmann, Jeanette, Samani, N. J., Rader, D.J. (Daniel), Harshfield, E., Houlston, R.S., Delgado, Graciela E., S. S. Verma (7646141), Franke, Andre, E. Zeggini (7632767), Zhang, WH, A. Singleton (7646228), Polychronakos, C, Franke, A, U. Thorsteinsdottir (7606031), S. G. Thompson (7646303), M. F. Keller (7646189), J. P. Bradfield (7646234), de Bakker, Paul I W, Allan, J. M., van 't Hof, Femke N. G., D. Chubb (7646255), Nikpay, Majid, M. A. Brown (1916698), Dehghan, Abbas, J. S. Kooner (7605356), Eisen, T, Chubb, Daniel, Harshfield, Eric, Whiffin, N, Freitag, Daniel, H. S. Markus (7626758), Tomlinson, I.P., Goldschmidt, H, Erdmann, J, Baas, A.F., Lange, Leslie A., Nielsen, S. F., Weidinger, S. (Stephan), Farrall, M. (Martin), Kuivaniemi, Helena, Ganesh, Santhi K., Reilly, Muredach, März, W. (Winfried), Huang, J., C. P. Nelson (7591670), Qu, Liming, Thorsteinsdottir, U, Wood, Angela M., De Andrade, M, Ritchie, M.D., Gottesman, O., Kastrati, A, Young, R. (Robin), J. M. Allan (7646246), Young, R., Müller-Nurasyid, M., van ‘t Hof, Femke N.G., Thorsteinsdottir, U. (Unnur), Psaty, B. M., J. Malinowski (7646147), Mueller-Nurasyid, M, Psaty, B.M. (Bruce), Easton, Douglas F., Hakonarson, H, Burgess, S, Ramond, A. (Anna), Marz, W, Luo, Y. (Yang), Pacheco, Jennifer A., Ritchie, Marylyn D., Carrell, D.S. (David), Howson, Joanna M.M., Ho, W.K., Kathiresan, S. (Sekar), S. A. Lubitz (7646210), Spackman, S, Smith, Nicholas L., Hemminki, Kari, Burgess, Stephen, D. C. Crawford (7646144), S. Nejentsev (7646273), D. Thompson (1262301), S. F. Nielsen (7646099), Bevan, S., Kooner, J. S., van 't Hof, F.N.G., Langefeld, Carl D., Lange, Leslie A, Lubitz, S.A. (Steven), Harris, T.B. (Tamara B.), Thompson, D., Sweeting, M, Iles, MM, Bown, M.J. (Matthew), M. Reilly (7609133), Ho, WK, Houlston, Richard S., Houlston, R. S., Ala-Korpela, M. (Mika), Li, Y. (Yong), Verma, S. S., Gottesman, Omri, A. Parsa (7626662), S. D. Thompson (7646222), Tomlinson, I.P. (Ian), J. Kettunen (7646180), Markus, H. S., Franco, O.H. (Oscar), Baas, A. F., Psaty, Bruce M., Ferreira, Manuel A., Jones, G. T., Grande, Peer, Smith, N.L., Al Shafi Majumder, A. (Abdullah), Law, MH, Wang, YF, S. Spackman (7646087), A. V. Smith (7605131), Hemminki, Kari,, Hall, A. S., Dunlop, Malcolm, Panoutsopoulou, K. (Kalliope), Howson, J. M. M., M. M. Iles (7646261), Allan, J.M., Tybjaerg-Hansen, A. (Anne), J. C. Bis (7625957), Ferreira, M.A., Freitag, DF, Matthew James Bown (7632455), Allan, James M., Jones, G.T., Wang, Y., Y. Li (696089), Franke, A., Parsa, Afshin, Bis, J.C. (Joshua), Hall, Alistair S., Farrall, M, Barbalic, M., Gottesman, R.F. (Rebecca), Hayward, N. K., Crosslin, D. R., van Rij, A., Staley, James R., Collins, F.S. (Francis), Porcu, E., Pacheco, J. A., Wang, Y, Lange, L. A., Henrion, Marc, Keller, MF, Zeggini, E, Crosslin, DR, S. Bevan (7626584), Parsa, A., Franco, Oscar H., Bown, Matthew J., Lange, LA, Bradfield, J.P. (Jonathan), Bottinger, EP, Smith, A.V., Lubitz, S.A., Qu, LM, Erdmann, J. (Jeanette), Angelantonio, E.D. (Emanuele Di), Crossman, D, W. K. Ho (7646081), Franceschini, N., Nalls, M. A., Thompson, S.D. (Susan D.), Wood, Angela M, Nelson, C. P., Keller, M. F., Scott, R.A. (Robert), Mitchell, GF, Langefeld, C.D., Qu, L., Smith, N.L. (Nicholas), Bis, J.C., Samani, N.J., Luo, Yang, Rader, Daniel J., Kathiresan, S, Walston, Jeremy D., Soranzo, N., Butterworth, A.S. (Adam), Crossman, D. (David), Collins, R, Sweeting, M., Porcu, E. (Eleonora), Burgess, S. (Stephen), Watkins, H. (Hugh), Hayward, N.K., Baurecht, H. (Hansjörg), Burgess, S., Markus, HS, Freitag, Daniel F., Iles, M. M., W. Zhang (820655), Rasmussen-Torvik, L.J., Thompson, D. (Deborah), Wood, A.M., Kleber, M.E. (Marcus), Tracy, R.P. (Russell), Bis, Joshua C., Huang, Jie, L. Qu (822458), Collins, R., Farrall, M., Li, Y, Hayward, Nicholas K., Parsa, A, Young, Robin, Easton, D. F., Chubb, D., Kullo, Iftikhar J., B. M. Psaty (7605224), A. S. Hall (7605176), Clarke, R. (Robert), D. Saleheen (7605173), Porcu, Eleonora, Grande, P. (Peer), Zeggini, E. (Eleftheria), Zeng, L, N. Soranzo (7608857), Chambers, J.C., M. Nikpay (7646114), L. J. Rasmussen-Torvik (7646174), J. C. Chambers (7605185), Iles, Mark M., K. Panoutsopoulou (7632989), M. Barbalic (7605845), Mitchell, Gary F., Nordestgaard, BG, Porcu, E, Kaptoge, Stephen, Lange, L.A. (Leslie), Crosslin, David R., Parsa, A. (Afshin), Soranzo, Nicole, Hofman, A. (Albert), Chambers, J.C. (John C.), J. A. Pacheco (7646177), O Reilly, M, Maerz, W, S. Weidinger (7646207), Morgan, G., Whiffin, Nicola, Scott, Robert A, Howson, Joanna M. M., Ganesh, S.K. (Santhi), Ala-Korpela, Mika, Scott, RA, Young, R, Müller-Nurasyid, Martina, Bishop, D.T., Jones, G.T. (Gregory), Crossman, David, H. Kuivaniemi (7646135), Kooner, Jaspal S., Willeit, Peter, de Bakker, Paul I.W., Kooner, JS, Tybjaerg-Hansen, Anne, Wang, Yufei, Nelson, C.P., Nordestgaard, Borge G., S. Baltic (7646198), Thorleifsson, Gudmar, Watkins, Hugh, Harris, T. B., D. S. Carrell (7646171), Thompson, D, F. N. G. van 't Hof (7646123), Malinowski, Jennifer, Walston, J.D., C. Polychronakos (7646231), J. D. Walston (7646291), A. S. Butterworth (7605158), Howson, J.M.M. (Joanna M.M.), Schunkert, Heribert, Saleheen, Danish, van 't Hof, Femke N G, Lange, L.A., Wilkinson, Ian B., Spackman, Sarah, N. J. Wareham (7608962), Baurecht, Hansjörg, Bradfield, Jonathan P., T. Assimes (7646279), Kathiresan, Sekar, Panoutsopoulou, K., Markus, Hugh S., Carrell, DS, Ferreira, M. A., Verma, Shefali S., Ferreira, M.A. (Manuel), Goel, A. (Anuj), M. Sweeting (7646084), van 't Hof, F. N. G., J. 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Thorleifsson (7606022), Zwart, J-A. (John-Anker), Nikpay, M, Felix, Janine, Keller, M.F., Böttinger, E.P., Thompson, S. D., Hakonarson, H., T. B. Harris (7605353), Ritchie, M.D. (Marylyn D.), Soranzo, N. (Nicole), N. Franceschini (7625954), Weidinger, Stephan, Baurecht, Hansjoerg, Peissig, PL, Staley, J. R., R. A. Scott (2840021), Pacheco, J.A. (Jennifer A.), Felix, J. F., Tracy, R., Brown, MA, Di Angelantonio, E, R. S. Houlston (7646258), Wareham, N.J. (Nick), Bakker, P.I.W. (Paul) de, Crawford, D.C., Lubitz, Steven A., Huang, J, Alam, D. S., Franco, OH, Gudnason, V. (Vilmundur), Kullo, I.J., M. Mueller-Nurasyid (7646213), Do, Ron, Kleber, Marcus, Schunkert, H., Reilly, M.P. (Muredach), Tomlinson, Ian P., Reilly, M, Kessler, T. (Thorsten), Franceschini, Nora, Goel, A., McPherson, R. (Ruth), Ritchie, MD, McCarty, C.A., Qu, L. (Liming), J. M. M. Howson (7646075), D. S. Alam (7646294), N. L. 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(Andre), Wareham, Nicholas J., Saleheen, D., Ramond, A, Kathiresan, Sekhar, Jones, Gregory T, Sweeting, Michael, Ligthart, S., Barbalic, Maja, Collins, Rory, Rader, DJ, Timpson, Nicholas J., Smith, A.V. (Davey), Hofman, Albert, Henrion, M., D. R. Crosslin (7646168), G. T. Jones (7627466), Thompson, Deborah, Ganesh, S.K., Wilkinson, I.B., Evans, David M., Tromp, G, Bruijn, L., Nejentsev, S. (Sergey), Kuivaniemi, H., Majumder, Abdullah Al Shafi, Do, R. (Ron), Nordestgaard, B. G., K. Stefansson (7606001), Gorski, M, Al Shafi Majumder, Abdullah, Kettunen, J, Majumder, AAS, M. Ala-Korpela (3442535), Gottesman, O, Assimes, T., McCarty, C. A., Barbalic, M, R. Clarke (7602407), Rasmussen-Torvik, L. J., Walston, JD, Whiffin, N. (Nicola), Tomlinson, IP, Willeit, P, Evans, D.M., Bruijn, Lucie, Nielsen, S.F., Morgan, G. (Gareth), de Bakker, P. I. W., Gudnason, V., Bis, J. C., Tracy, R, Baurecht, H, Polychronakos, C., Nielsen, S.F. (Sune), Bruijn, L. (Lucie), Böttinger, E. P., Bevan, S. (Steve), Kullo, I. J., De Bakker, PIW, McCarty, CA, Mitchell, G. F., Bishop, D. T., Carrell, D.S., Weidinger, S, Mueller-Nurasyid, Martina, Ala-Korpela, M., Samani, Nilesh J., M. A. Ferreira (7646201), J. Danesh (7605383), Hofman, Bert, Law, M.H. (Matthew H.), Watkins, H, Singleton, A., Huang, J. (Jie), Zhang, W. (Weihua), Mitchell, G.F., Van 't Hof, FNG, Nielsen, Sune F., Thompson, Susan D., Barbalic, M. (maja), Malinowski, J, Majumder, AA, Willeit, P., Soranzo, N, I. P. Tomlinson (7646237), Di Angelantonio, Emanuele, Dehghan, A, Li, Yunlei; id_orcid, Baas, A.F. (Annette), Easton, DF, Luo, Y., Staley, JR, A. Tybjaerg-Hansen (7605182), Kaptoge, S., Smith, N. L., Baurecht, H., Kleber, M., Hemminki, K, Zeggini, Eleftheria, Hemminki, K. (Kari), Dunlop, M, Sudman, M. (Marc), Kuivaniemi, H, Angelantonio, Emanuele Di, A. Dehghan (7626011), Brown, M.A. (Matthew), Ho, Weang Kee, Keller, M.F. (Margaux), Kaptoge, S, Baas, Annette F., Henrion, M. (Marc), Kessler, T, Rij, A.M. (Andre) van, Staley, J.R. (James R.), Peissig, P.L. (Peggy L.), Harris, T.B., Chowdhury, Rajiv, M. Henrion (7646249), Clarke, Robert, Chambers, JC, Ramond, Anna, Andrade, M. (Mariza) de, Baltic, S, Boettinger, Erwin P., Alam, D.S., L. Bruijn (7646195), Nejentsev, Sergey, Baltic, S. (Svetlana), Clarke, R., Thorsteinsdottir, Unnur, Kuivaniemi, H. (Helena), Chowdhury, R. (Rajiv), de Andrade, M., Angelantonio, E. D., W. Maerz (7646285), Kullo, I. (Iftikhar), Crossman, D., Hakonarson, H. (Hakon), Wilkinson, I.B. (Ian B.), Tromp, G., Ligthart, S, H. Schunkert (7603670), Tromp, Gerard, S. Kaptoge (7605374), Dunlop, M. (Malcolm), Gorski, M., Böttinger, Erwin P., Pacheco, JA, Harris, Tamara B., P. I. W. de Bakker (7605305), Timpson, N. J., Crosslin, D.R. (David), Bradfield, J.P., Thorleifsson, G, Timpson, NJ, Law, Matthew H., Nordestgaard, B.G. (Børge), Gudnason, Vilmundur, Bradfield, JP, H. Hakonarson (7609127), N. K. Hayward (7646270), Goldschmidt, H., Singleon, Andrew, P. Grande (7646102), Farrall, Martin, Wood, A. M., V. Gudnason (7605347), Crawford, Dana C., Do, R, Verma, S.S., Houlston, RS, Morgan, Gareth, Singleton, A. (Andrew), J. F. Felix (7625948), R. Collins (7159586), Zeng, LY, Clarke, R, Thompson, S.D., A. Franke (7412741), Dehghan, A. (Abbas), Van Rij, A, Smith, A. V., Rader, D.J., Panoutsopoulou, K, Tybjærg-Hansen, A., Bruijn, L, Nalls, MA, Kastrati, Adnan, S. K. Ganesh (7626842), Angelantonio, E.D., Baltic, S., R. Tracy (7646282), Danesh, John, A. Kastrati (7646288), Thorsteinsdottir, U., Easton, D.F. (Douglas), Harshfield, E. (Eric), Kastrati, A. (Adnan), Verma, SS, Zeng, L., März, W., Howson, JMM, Thorleifsson, G., Iles, M.M. (Mark M.), R. McPherson (7605974), Spackman, S. (Sarah), Do, R., Rader, D. J., D. J. Rader (7605215), R. Chowdhury (7646300), Danesh, J. (John), R. Young (7646078), P. L. Peissig (7646156), Brown, Matthew A., Psaty, BM, Verma, S.S. (Shefali S.), Zeggini, E., Schunkert, H. (Heribert), Thompson, S.G. (Simon), McPherson, Ruth, Chowdhury, R, J. Huang (2342368), Jones, Gregory T., Smith, NL, Psaty, B.M., Assimes, Themistocles, Zhang, Weihua, O. H. Franco (7625993), Brown, M.A., Hofman, A, A. Hofman (4269889), Hopewell, Jemma C, H. Watkins (7602419), Kastrati, A., Hall, A.S., Wood, A.M. (Angela), Ala-Korpela, M, C. D. Langefeld (7646192), Ho, W. K., Ganesh, S. K., Lubitz, S. A., Hopewell, JC, Nejentsev, S, Y. Luo (1398985), Maerz, Winfried, Baas, AF, C. A. McCarty (7646159), N. Whiffin (7646252), Hopewell, J., Houlston, R. (Richard), Timpson, N.J. (Nicholas), Allan, J.M. (James), Alam, DS, Kaptoge, S. (Stephen), Delgado, Graciela E, Ho, W.K. (Weang Kee), Sudman, M, Thorsteindottir, Unnur, Kettunen, J., Langefeld, C. D., Tomlinson, I. P., Ganesh, SK, Stefansson, Kari +874 morecore +5 more sourcesAlpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors
Frontiers in Immunology, 2018 While interleukin (IL)-1β is a potent pro-inflammatory cytokine involved in host defense, high levels can cause life-threatening sterile inflammation including systemic inflammatory response syndrome.Kathrin Siebers, Bijan Fink, Anna Zakrzewicz, Alisa Agné, Katrin Richter, Sebastian Konzok, Andreas Hecker, Sven Zukunft, Mira Küllmar, Jochen Klein, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh, Thomas Timm, Katherina Sewald, Winfried Padberg, Nupur Aggarwal, Walee Chamulitrat, Sentot Santoso, Wendy Xia, Sabina Janciauskiene, Veronika Grau +21 moredoaj +1 more sourceInterleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding [PDF]
, 2009 Background: Atherosclerosis is an inflammatory process that develops in individuals with known risk factors that include hypertension and hyperlipidaemia, influenced by diet.Dower, S., Zoe Brookes, Nicholas J Alp, Francis, Sheila, Steven Dower, David C Crossman, Brookes, Zoe, Francis, S., Shaw, Gary, Shaw, G., Crossman, D.C., Gary Shaw, Sheila Francis, Graham, Delyth, Brookes, Z., Alp, N.J., Crossman, David C., Chamberlain, J., Delyth Graham, Dower, Steven, Graham, D., Xu, A., Janet Chamberlain, Alp, Nicholas J., Xu, Aimin, Chamberlain, Janet +25 morecore +1 more sourceStructural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.James K. Fields, James K. Fields, James K. Fields, Sebastian Günther, Eric J. Sundberg, Eric J. Sundberg, Eric J. Sundberg +6 moredoaj +1 more sourceMagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov +7 morewiley +1 more sourcePrimary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]
, 2012 Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate Knight, M.M., A. K. T. Wann, Wann, A.K.T., Knight, MM, Wann, AKT, M. M. Knight +5 morecore +1 more source
