Results 11 to 20 of about 196,653 (259)
Effects of Recombinant Interleukin 1 and Interleukin 2 on Human Keratinocytes [PDF]
, 1989 The effects of recombinant interleukin 1 alpha and beta, as well as recombinant interleukin 2, on human keratinocyte proliferation were studied in serum-containing as well as defined media.
Cua, Anastasia B +3 more
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Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study
Critical Care Explorations, 2022 OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD +15 more
doaj +1 more source
Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
Frontiers in Immunology, 2019 The role of interleukin-1 in the regulation of humoral responses is poorly documented, in contrast to its role in inflammation. Recent findings suggest there is an interleukin-1 axis in the follicular T cell control of B cell responses, involving ...
Paul-Gydéon Ritvo +2 more
doaj +1 more source
Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status [PDF]
, 2019 Aims: Heart failure is a clinical syndrome characterized by subclinical systemic inflammation and immune system activation associated with iron deficiency.
Corrao S. +10 more
core +1 more source
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core +4 more sources
Biology of the Interleukin-1 Receptor
Journal of Investigative Dermatology, 1990 The biological effects of the two interleukin-1s on cells of connective tissue origin are mediated by specific cell-surface receptors. Molecular cloning studies have revealed that these receptors are identical in protein sequence to the IL-1 receptors on cells of the T-lymphocyte lineage. The functional interleukin-1 receptor on T-cells and fibroblasts
Rebecca A. Blanton +7 more
openaire +3 more sources
Frontiers in Drug Research and Development for Inflammatory Bowel Disease
Frontiers in Pharmacology, 2017 Inflammatory bowel disease (IBD) is idiopathic, lifelong, immune-mediated diseases, for which curative therapies are not yet available. In the last 15 years, the introduction of monoclonal antibodies targeting tumor necrosis factor-α, a cytokine playing ...
Diego Currò +2 more
doaj +1 more source
What Is IL-1 for? The Functions of Interleukin-1 Across Evolution
Frontiers in Immunology, 2022 Interleukin-1 is a cytokine with potent inflammatory and immune-amplifying effects, mainly produced by macrophages during defensive reactions. In mammals, IL-1 is a superfamily of eleven structurally similar proteins, all involved in inflammation or its ...
Diana Boraschi +2 more
doaj +1 more source
Interleukin-38 and cardiovascular pathology: literature review [PDF]
КардиоСоматика, 2023 Cardiovascular pathology is a leading cause of morbidity and mortality. An important task of modern cardiology is the search and study of new biological markers. Scientists’ interest is actively focused on the study of interleukin-38.
Amina M. Alieva +4 more
doaj +1 more source
Inflammation as a Central Mechanism in Alzheimer\u27s Disease [PDF]
, 2018 Alzheimer\u27s disease (AD) is a progressive neurodegenerative disorder that is characterized by cognitive decline and the presence of two core pathologies, amyloid β plaques and neurofibrillary tangles.
Bemiller, Shane M. +5 more
core +2 more sources