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Granulocytes and their Involvement in the Foreign Body Response to Biomaterials and Tissue Repair. [PDF]

In Vivo
Barbeck M, Jung O.
europepmc   +1 more source

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Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.

International Reviews of Immunology, 1998
IL-1 (IL-1 alpha or IL-1 beta) is the prototypic "multifunctional" cytokine. Unlike the lymphocyte and colony stimulating growth factors, IL-1 affects nearly every cell type, and often in concert with other cytokines or small mediator molecules. Although some lymphocyte and colony stimulating growth factors may be therapeutically useful, IL-1 is a ...
C. Dinarello
semanticscholar   +3 more sources

Blocking interleukin-1 receptors

International Journal of Clinical & Laboratory Research, 1994
During inflammation, injury, immunological challenge or infection, interleukin-1 appears to mediate, in part, the pathogenesis, of disease. Most studies on interleukin-1 are derived from experiments in which bacterial products, such as endotoxins from Gram-negative bacteria or exotoxins from Gram-positive organisms, are used to stimulate macrophagic ...
C. Dinarello
semanticscholar   +3 more sources

The family of the interleukin‐1 receptors

Immunological Reviews, 2018
SummaryThe extracellular forms of the IL‐1 cytokines are active through binding to specific receptors on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand‐binding receptor chain. For signaling to take place, a non‐binding accessory chain is recruited into a heterotrimeric complex.
D. Boraschi, P. Italiani, Sabrina Weil, Michael U. Martin   +3 more
semanticscholar   +4 more sources

Interleukin-1 receptors.

European Cytokine Network, 1994
J. Sims, S. Dower
semanticscholar   +2 more sources

The interleukin 1 receptor

Immunology Today, 1989
The diverse biological activities of interleukin 1 (IL-1) have attracted interest from a wide range of biological disciplines ~ After systemic injection into a variety of animals, it seems that IL-1 affects nearly every organ system. Interested parties fall into two groups: those studying the potential beneficial effects of IL-1 on host defense ...
C A, Dinarello, B D, Clark, A J, Puren, N, Savage, P M, Rosoff   +4 more
openaire   +2 more sources