Results 271 to 280 of about 503,937 (310)

Interleukin-1 and interleukin-1 receptor antagonist.

Nutrition (Burbank, Los Angeles County, Calif.), 1996
Cytokines are produced in disease or during immunologic challenge. Some cytokines increase host resistance to disease whereas others trigger inflammatory processes. Interleukin 1 (IL-1) and tumor necrosis factor (TNF) are pro-inflammatory cytokines that affect nearly every cell either alone or in a synergistic fashion.
openaire   +1 more source

The interleukin-1/interleukin-1-receptor interaction

Annales de l'Institut Pasteur / Immunologie, 1987
H R, MacDonald, J W, Lowenthal
openaire   +2 more sources

The interleukin-1 receptor complex and interleukin-1 signal transduction.

European cytokine network, 1997
The aim of this mini-review is to give an update on the current developments concerning the IL-1 plasma membrane receptor complex and the modes of signal transduction through the plasma membrane. The mechanisms of signal generation at the cytosolic side of the plasma membrane will be summarized.
M U, Martin, W, Falk
openaire   +1 more source

Induction of interleukin-1 and interleukin-1 receptor antagonist.

Seminars in oncology, 1997
Drugs that affect the production or action, or both, of the pleiotropic inflammatory cytokine interleukin-1 (IL-1) are predicted to have a significant impact on a variety of human diseases. The biochemical properties of IL-1 and the IL-1 receptor antagonist, the mechanism for their production, and the factors that regulate their release are discussed ...
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Characterization of Interleukin-1 Receptors

1987
The inflammatory response to disease and injury involves a variety of physiological events, amongst which are fever, release of acute phase proteins, the immune response and connective tissue breakdown and remodeling (1). Recent advances in analytical methods, in particular molecular biology, have led to the characterization of several polypeptides ...
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Interleukin-1 and its receptor.

Critical reviews in immunology, 1989
Interleukin-1 (IL-1) is a polypeptide that is produced during infection, injury, or immunologic challenge. There are two molecular forms, IL-1-beta and IL-1-alpha, and despite only a 26% amino acid homology, both forms induce a wide variety of biological changes.
C A, Dinarello, N, Savage
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Interleukin-1 receptor antagonism.

Seminars in nephrology, 1997
Interleukin-1 (IL-1) is a pro-inflammatory cytokine that exerts a wide range of biological effects. The recently identified IL-1 receptor antagonist (IL-1ra) has provided a tool for blocking IL-1 activity in vivo, leading to a detailed understanding of the role of this cytokine in the inflammatory response.
D J, Nikolic-Paterson, H Y, Lan, R C, Atkins   +2 more
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Interleukin-1 receptor antagonist

2000
Interleukin-1 (IL-1) is a proinflammatory cytokine produced by a wide variety of cell types with an equally pleiotropic range of activities including the induction of fever, hypotension, adhesion molecule expression, neutrophilia, cartilage destruc­tion, prostanoid production, and induction of the expression of a number of other cytokines. Two forms of
openaire   +1 more source

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod A Dudakov, Alan M Hanash, Marcel R M van den Brink   +2 more
exaly  

Historical overview of the interleukin-6 family cytokine

Journal of Experimental Medicine, 2020
Sujin Kang, Masashi Narazaki, Hozaifa Metwally   +2 more
exaly