Results 61 to 70 of about 304,930 (167)

Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage

Viruses, 2019
Multisystemic inflammation in pigs affected by porcine circovirus type 2 (PCV2) indicates the disordered expression of inflammatory cytokines. However, the PCV2-induced expression profile of inflammation cytokines and its regulating mechanism remain ...
Shunli Yang, Baohong Liu, Shuanghui Yin, Youjun Shang, Xinming Zhang, Muhammad Umar Zafar Khan, Xiangtao Liu, Jianping Cai   +7 more
doaj   +1 more source

IL-38: A New Player in Inflammatory Autoimmune Disorders

Biomolecules, 2019
Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36
Lihui Xie, Zhaohao Huang, He Li, Xiuxing Liu, Song Guo Zheng, Wenru Su   +5 more
doaj   +1 more source

Molecular Mechanism of NLRP3 Inflammasome in Inflammatory Diseases and Tumors

Immunity, Inflammation and Disease
The nucleotide‐binding and oligomerization domain‐like receptors (NLRs) are pattern recognition receptors. Nucleotide‐binding oligomerization domain‐like receptor family pyrin domain‐containing 3 (NLRP3), a member of the NLRs family, can form a protein ...
Le‐Lan Gong, He‐Jiang Zhou, Quan‐Ming Zhao, Ning Xu, Feng‐Chang Huang, Ling‐Yan Su, Wen‐Liang Li   +6 more
doaj   +1 more source

Inflammasome in Intestinal Inflammation and Cancer

Mediators of Inflammation, 2013
The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD-) like receptors (NLRs), leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1.
Tiago Nunes, Heitor S. de Souza
doaj   +1 more source

Interactions Between Candida albicans and Host
Interações entre Candida albicans e Hospedeiro

Semina: Ciências Biológicas e da Saúde, 2011
Candida albicans can cause grave infections in patients who are immunocompromised by diseases, by surgery, or by immunesupresive therapy. The high levels of morbidity and mortality resulting from those infections in hospitalized patients show that C ...
Tatiane De Rossi, Marcell Alysson Batisti Lozovoy, Rosiane Valeriano da Silva, Eduardo Vignoto Fernandes, Thais Herrero Geraldino, Ivete Conchon Costa, Halha Ostrenski Saridakis, Maria Angelica Ehara Watanabe, Ionice Felipe   +8 more
doaj  

Ligands and Receptors of the Interleukin-1 family in immunity and disease

Frontiers in Immunology, 2013
Cecilia eGarlanda, Alberto eMantovani, Alberto eMantovani   +2 more
doaj   +1 more source

Microglia-orchestrated neuroinflammation and synaptic remodeling: roles of pro-inflammatory cytokines and receptors in neurodegeneration

Frontiers in Cellular Neuroscience
Microglia, the innate immune cells of the central nervous system (CNS), play essential roles in maintaining neural homeostasis through dynamic interactions with neurons and other brain structures.
Guang Yang, Guang Yang, Xiao Xu, Waimao Gao, Xingyu Wang, Yan Zhao, Ying Xu   +6 more
doaj   +1 more source

P2X7 receptor mediates activation of microglial cells in prostate of chemically irritated rats

International Brazilian Journal of Urology, 2013
Purpose Evidence shows that adenosine triphosphate (ATP) is involved in the transmission of multiple chronic pain via P2X7 receptor. This study was to investigate the P2X7 and microglial cells in the chronic prostatitis pain.
Heng Zhang, Limei Liu, Zhong Yang, Jinhong Pan, Zhiwen Chen, Qiang Fang, Weibin Li, Longkun Li, Gengsheng Lu, Zhansong Zhou   +9 more
doaj  

Interleukin-1 Receptors Are Differentially Expressed in Normal and Psoriatic T Cells

Mediators of Inflammation, 2014
Attila Bebes, Ferenc Kovács-Sólyom, Judit Prihoda, Róbert Kui, Lajos Kemény, Rolland Gyulai   +5 more
doaj   +1 more source

Associations of serum sTREM-1 and sTREM-2 with mortality and neurological prognosis in patients resuscitated from cardiac arrest: a machine learning-based approach. [PDF]

Front Med (Lausanne)
Wang L, Chen P, Chen Y, Fan Z, Yu D, Zhang W, Fu B, Gong P.   +7 more
europepmc   +1 more source