Results 41 to 50 of about 478,975 (311)

Expression of hormonal receptors and Toll-like receptors in cultured canine uterine explants with pseudoplacentational endometrial hyperplasia and bacterial-elicited endometrial inflammation.

PLoS ONE
Pseudoplacentational endometrial hyperplasia (PEH) is a common uterine lesion in dogs. A high frequency of pyometra has been associated with PEH in dogs, suggesting that PEH might be related to the pathogenesis of pyometra.
Clarissa Helena Santana, Monique Ferreira Silva Souza, Laice Silva, Lucas Dos Reis Souza, Ayisa Rodrigues Oliveira, Álan Maia Borges, Tatiane Paixão, Renato Lima Santos   +7 more
doaj   +1 more source

Augmenting the Antitumor Efficacy of Natural Killer Cells via SynNotch Receptor Engineering for Targeted IL-12 Secretion

Current Issues in Molecular Biology
Natural killer (NK) cells are crucial components of innate immunity, known for their potent tumor surveillance abilities. Chimeric antigen receptors (CARs) have shown promise in cancer targeting, but optimizing CAR designs for NK cell functionality ...
Ali Ahmadnia, Saeed Mohammadi, Ahad Yamchi, Mohamad Reza Kalani, Touraj Farazmandfar, Ayyoub Khosravi, Ali Memarian   +6 more
doaj   +1 more source

Expression of interleukin 2 receptors on activated human B cells. [PDF]

, 1984
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF, Depper, JM, Goldman, CK, Greene, WC, Korsmeyer, SJ, Leonard, WJ, Robb, RJ, Sharrow, SO, Waldmann, TA   +8 more
core  

Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. [PDF]

, 2019
Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming.
Canter, Robert J, Gingrich, Alicia A, Modiano, Jaime F   +2 more
core   +2 more sources

Clinical Features of Candidiasis in Patients With Inherited Interleukin 12 Receptor β1 Deficiency [PDF]

Clinical Infectious Diseases, 2013
Interleukin 12Rβ1 (IL-12Rβ1)-deficient patients are prone to clinical disease caused by mycobacteria, Salmonella, and other intramacrophagic pathogens, probably because of impaired interleukin 12-dependent interferon γ production. About 25% of patients also display mucocutaneous candidiasis, probably owing to impaired interleukin 23-dependent ...
Ouederni, Monia, Sanal, Ozden, Ikinciogullari, Aydan, Tezcan, Ilhan, Dogu, Figen, Sologuren, Ithaisa, Pedraza-Sanchez, Sigifredo, Keser, Melike, Tanir, Gonul, Nieuwhof, Chris, Colino, Elena, Kumararatne, Dinakantha, Levy, Jacov, Kutukculer, Necil, Aytekin, Caner, Herrera-Ramos, Estefania, Bhatti, Micah, Karaca, Neslihan, Barbouche, Mohamed-Ridha, Broides, Arnon, Goudouris, Ekaterini, Luis Franco, Jose, Parvaneh, Nima, Reisli, Ismail, Strickler, Alexis, Shcherbina, Anna, Somer, Ayper, Segal, Anthony, Angel-Moreno, Alfonso, Luis Lezana-Fernandez, Jose, Bejaoui, Mohamed, Bobadilla-del Valle, Miriam, Kachboura, Salem, Sentongo, Timothy, Ben-Mustapha, Imen, Bustamante, Jacinta, Picard, Capucine, Puel, Anne, Boisson-Dupuis, Stephanie, Abel, Laurent, Casanova, Jean-Laurent, Rodriguez-Gallego, Carlos   +41 more
openaire   +5 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies

Haematologica, 2016
We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted ...
Letizia Muccio, Alice Bertaina, Michela Falco, Daniela Pende, Raffaella Meazza, Miguel Lopez-Botet, Lorenzo Moretta, Franco Locatelli, Alessandro Moretta, Mariella Della Chiesa   +9 more
doaj   +1 more source

Il-15/il-15rα signalling and synaptic transmission: a crosstalk between the immune and the nervous system? [PDF]

, 2019
Immune and nervous system have been traditionally considered separately, but from ‘90s many studies had unraveled the deep interconnection and interdependence between these two systems, enough to coin the term “neuroimmune system” to define this ...
Carbonari, Laura
core  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Natural Killer Cells: Development, Maturation, and Clinical Utilization

Frontiers in Immunology, 2018
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization.
Alex M. Abel, Alex M. Abel, Chao Yang, Chao Yang, Monica S. Thakar, Monica S. Thakar, Subramaniam Malarkannan, Subramaniam Malarkannan, Subramaniam Malarkannan, Subramaniam Malarkannan, Subramaniam Malarkannan   +10 more
doaj   +1 more source