Results 31 to 40 of about 5,515,432 (305)
Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model. [PDF]
PLoS ONE, 2016 The need for new options for chronic lung diseases promotes the research on stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can modulate lung inflammation, but the data on cellular processes involved in early airway ...
Konrad Urbanek +11 more
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Basophils in pruritic skin diseases
Frontiers in Immunology, 2023 Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic dermatitis, bullous pemphigoid, chronic spontaneous urticaria and ...
Daniela Wiebe +6 more
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Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
, 2003 Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda +10 more
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The role of IL-13 gene polymorphism in the exacerbation of Asthma severity
Sokoto Journal of Medical Laboratory Science, 2023 Asthma is a chronic airway inflammatory disorder characterized by persistent airway inflammation, obstruction, and hyper-responsiveness. The role of cytokines, particularly Interleukin-13 (IL-13), in the pathogenesis of asthma has been extensively ...
Kabir, I.M.1, Ibrahim, S.2, Badamasi, I. M.3, Ibrahim H.S.4, Bala J.A.1, Aliyu I.A1*.
doaj
Physiological Reports, 2019 Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza +3 more
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Immune regulation in pathophysiology and targeted therapy for itch in atopic dermatitis
Dermatologica Sinica, 2016 Itch is an unpleasant perception that provokes one to desire to scratch. It results from the activation of free nerve endings by noxious stimuli in the skin.
Chih-Hung Lee
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Reduced interleukin-4 receptor α expression on CD8+ T cells correlates with higher quality anti-viral immunity. [PDF]
PLoS ONE, 2013 With the hope of understanding how interleukin (IL)-4 and IL-13 modulated quality of anti-viral CD8(+) T cells, we evaluated the expression of receptors for these cytokines following a range of viral infections (e.g.
Danushka K Wijesundara +3 more
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Interleukin-13 Receptor Alpha 2-Targeted Glioblastoma Immunotherapy [PDF]
BioMed Research International, 2014 Glioblastoma (GBM) is the most lethal primary brain tumor, and despite several refinements in its multimodal management, generally has very poor prognosis. Targeted immunotherapy is an emerging field of research that shows great promise in the treatment of GBM.
Sadhak Sengupta +3 more
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Allergy MedicineAtopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. It usually develops in childhood and may persist into adulthood. Dupilumab is a fully human monoclonal antibody directed against interleukin-4R-alpha, the common chain ...
Jing Zhang +4 more
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Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody
Cell Reports, 2014 Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Here, we report the crystal structure of the IL-3 receptor α chain (IL3Rα) in complex with the anti-leukemia ...
Sophie E. Broughton +18 more
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