Results 251 to 260 of about 439,419 (286)

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

Advanced Science, EarlyView.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang, Yongrui Hai, Xintong Lu, Ye Chen, Bingjie Zhang, Renming Fan, Jiarui Dou, Jiaxin Yan, Shuo Fu, Wen Zhang, Junke Song, Gaofei Wei   +11 more
wiley   +1 more source

Molecular mechanisms of acute inflammation: systemic responses and kidney-specific pathophysiology. [PDF]

Function (Oxf)
Chelangarimiyandoab F, Lavoie JC, Flamand N, Cordat E, Breton S.   +4 more
europepmc   +1 more source

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

Advanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li, Penghui Wei, Yuanbo Pan, Hongjia Zheng, Jiajun Hu, Qianxi Chen, Zhongyuan Shen, Yongrui Hu, Jiajun Wu, Fuxin Lin, Fuxiang Chen, Chenyu Ding, Wenhua Fang, Yuanxiang Lin, Dezhi Kang, Yuxiang Gu, Yang Zhu, Dengliang Wang   +17 more
wiley   +1 more source

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction. [PDF]

Front Immunol
Vella R, Panci D, Carini F, Malta G, Vieni S, David S, Albano GD, Puntarello M, Zerbo S, Argo A.   +9 more
europepmc   +1 more source

Oral microbiota-driven immune modulation along the oral-gut axis: from local signals to systemic inflammation. [PDF]

NPJ Biofilms Microbiomes
Li C, Fan Y, Chen X.
europepmc   +1 more source

Molecular mechanisms of neutrophil regulatory network in anti-Candida infection. [PDF]

Front Immunol
Xu Y, Cheng R, Li W, Yu W, Chen C.
europepmc   +1 more source

The neuro-immune insights of itch: peripheral mechanisms and central glial contributions. [PDF]

Cell Mol Biol Lett
Li Z, Yu N, Feng S, Wang X, Chu YX, Liu X.   +5 more
europepmc   +1 more source

Expression Analysis of <i>VEGF</i>-Related Hub Genes and Pathways in Breast Cancer: A Comprehensive Bioinformatics Analysis. [PDF]

Iran J Med Sci
Khoshandam M, Rahmanian M, Hedayati Goudarzi MT, Soltaninejad H, Babashah S, Khoshandam M.   +5 more
europepmc   +1 more source