Results 81 to 90 of about 289,750 (311)

Trypanosomiasis-induced Th17-like immune responses in carp

, 2010
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade, Verburg-van Kemenade, B.M.L., Chadzinska Magdalena, Wiegertjes Geert F., Chadzinska, M.K., Huub F. J. Savelkoul, Scheer Marleen, Savelkoul, H.F.J., Scheer, M.H., Geert F Wiegertjes, Savelkoul Huub F. J., Bird, S., Maria J. S. L. Pontes, Ribeiro, Carla M. S., B. M. Lidy Verburg-van Kemenade, Wiegertjes, G.F., Savelkoul, Huub F. J., Carla M S Ribeiro, Scheer, Marleen, Marleen Scheer, Verburg-van Kemenade B. M. Lidy, Steve Bird, Maria J S L Pontes, Huub F J Savelkoul, Pontes, Maria J. S. L., Verburg-van Kemenade, B. M. Lidy, Ribeiro, C.M.S., Wiegertjes, Geert F., Bird Steve, Magdalena Chadzinska, Carla M. S. Ribeiro, Pontes, M.J.S.L., Ribeiro Carla M. S., Chadzinska, Magdalena, Pontes Maria J. S. L., Bird, Steve, Geert F. Wiegertjes   +36 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms [v1; ref status: indexed, http://f1000r.es/3ny]

F1000Research, 2014
CD4+ T cells provide a neuro-immunological link in the regulation of adult hippocampal neurogenesis, but the exact mechanisms underlying enhanced neural precursor cell proliferation and the relative contribution of different T helper (Th) cell subsets ...
Johannes Niebling, Annette E. Rünker, Sonja Schallenberg, Karsten Kretschmer, Gerd Kempermann   +4 more
doaj   +1 more source

Interleukin 17 Receptor A Modulates Monocyte Subsets and Macrophage Generation In Vivo

PLoS ONE, 2014
Interleukin (IL)-17A signaling via Interleukin 17 receptor A (Il17ra) contributes to the inflammatory host response by inducing recruitment of innate immune cells, but also plays a role in homeostatic neutrophilic granulocyte regulation. Monocytes, the other main innate immune cell, have a longer life span and can pursue multiple differentiation ...
Shuwang Ge, Barbara Hertel, Nathan Susnik, Song Rong, Anna M Dittrich, Roland Schmitt, Hermann Haller, Sibylle von Vietinghoff   +7 more
openaire   +3 more sources

Interleukin-17/Interleukin-17 Receptor-Mediated Signaling Is Important for Generation of an Optimal Polymorphonuclear Response againstToxoplasma gondiiInfection [PDF]

Infection and Immunity, 2005
ABSTRACTWe investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity againstToxoplasma gondii. IL-17R−/−mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear ...
Michelle N, Kelly, Jay K, Kolls, Kyle, Happel, Joseph D, Schwartzman, Paul, Schwarzenberger, Crescent, Combe, Magali, Moretto, Imtiaz A, Khan   +7 more
openaire   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease

, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core  

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source