Results 11 to 20 of about 299,590 (247)
Mediators of Inflammation, 2016 The cytokines interleukin-11 (IL-11) and IL-6 are important proteins with well-defined pro- and anti-inflammatory functions. They activate intracellular signaling cascades through a homodimer of the ubiquitously expressed signal-transducing β-receptor ...
Juliane Lokau +2 more
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Circulating endothelial progenitor cells and inflammatory markers in type 1 diabetes after an acute session of aerobic exercise [PDF]
Archives of Endocrinology and MetabolismObjective: To determine circulating endothelial progenitor cells (EPC) counts and levels of inflammatory markers in individuals with and without type 1 diabetes mellitus (T1DM) in response to an intense aerobic exercise session. Subjects and methods: In
Patrícia Martins Bock +11 more
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The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells
Journal of Inflammation Research, 2021 Mansour Haddad Faculty of Pharmacy, Philadelphia University, Amman, JordanCorrespondence: Mansour Haddad Email Dr.man.haddad@gmail.comBackground: Various factors trigger the inflammatory response and cytokine activation in skeletal muscle.
Haddad M
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Autoinflammatory disease: clinical perspectives and therapeutic strategies
Inflammation and Regeneration, 2022 The molecular platforms of the innate immune system are essential to recognize pathologic external factors that are crucial to differentiate these danger signals from host motifs.
Atsushi Kawakami +4 more
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Adenosine-dependent regulation of paracrine factors expression in human venous blood monocytes
Бюллетень сибирской медицины, 2011 The flow cytometry analysis of human peripheral blood monocytes separated by a two step density gradient centrifugation is reported. The expression of mRNA level of adenosine receptor (AdoR) subtypes (A1, A2A, A2B and A3) and interleukin 6 (IL-6 ...
S. V. Ryzhov +10 more
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Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update [PDF]
Annals of the Rheumatic Diseases, 2023 Targeting interleukin (IL)-6 has become a major therapeutic strategy in the treatment of immune-mediated inflammatory disease. Interference with the IL-6 pathway can be directed at the specific receptor using anti-IL-6Rα antibodies or by directly inhibiting the IL-6 cytokine.
Daniel Aletaha +43 more
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Academic Science Journal, 2023 Cytokines are important mediators in inflammatory disorders that affect the entire body. Signaling molecules called pro-inflammatory cytokines, also known as inflammatory cytokines, are released by the immune system cells including macrophages and T ...
Khalid Shaalan Sahab +2 more
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Stabilized Interleukin-6 receptor binding RNA aptamers [PDF]
RNA Biology, 2013 Interleukin-6 (IL-6) is a multifunctional cytokine that is involved in the progression of various inflammatory diseases, such as rheumatoid arthritis and certain cancers; for example, multiple myeloma or hepatocellular carcinoma. To interfere with IL-6-dependent diseases, targeting IL-6 receptor (IL-6R)-presenting tumor cells using aptamers might be a ...
Cindy, Meyer +6 more
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Nature Communications, 2017 Interleukin-6 (IL-6) is increased in obesity and activates T cells to promote inflammation. Here, Xuet al. use mice that lack IL-6 receptors on T cells to uncover the temporal and tissue-specific effects of classic and trans IL-6 signalling on ...
Elaine Xu +8 more
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Physiological Reports, 2019 Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza +3 more
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