Receptors, interleukin-6 - Open Access .click

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Interleukin-6 receptor-interleukin-6 fusion proteins with enhanced interleukin-6 type pleiotropic activities.

European cytokine network, 1998
An sIL-6R/IL-6 chimera, directly fusing the natural forms of soluble IL-6 receptor and IL-6, as found in human body fluids, was produced in transfected human cells. The secreted p85 glycoprotein was active at a concentration of 120 pM to produce growth-arrest and spindleoid differentiation of murine melanoma F10.9 cells, which do not respond to IL-6 ...
J, Chebath +10 more
openaire +1 more source

Interleukin-6 receptor signaling. I. gp80 and gp130 receptor interaction in the absence of interleukin-6.

European cytokine network, 1999
Interleukin-6 (IL-6) is used as a growth factor by various tumor cells. It binds to a gp80 specific receptor (IL-6R) and then to a gp130 transducing chain. Both receptor chains are released as soluble functional proteins which circulate in biological fluids.
J P, Gaillard +4 more
openaire +1 more source

Biology and therapeutic potential of interleukin-10

Journal of Experimental Medicine, 2020
Anne O'Garra, Margarida Saraiva, Paulo Vieira +2 more
exaly

[Interleukin-6/soluble interleukin-6 receptor].

Nihon rinsho. Japanese journal of clinical medicine, 2000
A, Yokoyama, K, Hiwada
openaire +1 more source

Interleukin-22: Immunobiology and Pathology

Annual Review of Immunology, 2015
Jarrod Dudakov, Alan Hanash
exaly

Signaling and Function of Interleukin-2 in T Lymphocytes

Annual Review of Immunology, 2018
Sarah Ross, Doreen Cantrell
exaly

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

Circulation, 2012
Tom Thurén, Peter Libby, Brendan Everett +2 more
exaly

Interleukin-4 and lnterleukin-13: Their Similarities and Discrepancies

International Reviews of Immunology, 1998
Jacques Banchereau, P Chomarat
exaly