Results 141 to 150 of about 26,234 (229)

Molecular recognition by Ig-like receptors, KIRs and Fc gamma Rs

, 2016
Structural studies by us and other groups have shown that Killer cell Ig-like receptors (KIRs) and Fc gamma receptors (Fc gammaR) have a similar, unique topology (intermediate between I set and C2 set). In order to gain further insight into molecular recognition by these receptors, we have used surface plasmon resonance (SPR) to analyze the kinetic and
Maenaka, K, Van Der Merwe, P, Stuart, D, Sondermann, P, Jones, E   +4 more
openaire   +1 more source

[Role of killer cell immunoglobulin-like receptors (KIR) in human diseases].

Postepy higieny i medycyny doswiadczalnej (Online), 2004
The genetics and physiological role of killer cell immunoglobulin-like receptors (KIR) are briefly reviewed. Haplotype polymorphism of KIR genes resulting in different proportions of genes coding for activatory and inhibitory receptors is emphasized. The participation of KIR molecules in the reactions of natural killer (NK) cells and subpopulations of ...
openaire   +1 more source

Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition. [PDF]

J Immunother Cancer
Lee SN, Arseneau RJ, Arnason T, Boudreau JE.   +3 more
europepmc   +1 more source

Gene Regulatory Programs of NK Cells Show That NCAM1 (CD56) and KIRs Are Controlled by Genetically Polymorphic Distal Regulatory Elements. [PDF]

Eur J Immunol
Salem MA, Varkey A, Estrada MD, Sharma K, Eisele CD, Chakravarti N, Lee DA, Freud AG, Mundy-Bosse BL, Collins PL.   +9 more
europepmc   +1 more source

<i>KIR AA</i> individuals possess strong inhibitory <i>KIR</i> alleles alongside HLA ligands that are protective against leukemia in the Chinese population. [PDF]

Front Genet
Deng Z, Zhen J, Li Y, Liang S, Zhang M, Cai S, Jiang R, Yang Z, Yu Q, Wang J, Liu J.   +10 more
europepmc   +1 more source

Post-translational modification of NK cell receptors offers clues to antigenic specificity riddle. [PDF]

Front Immunol
Ustiuzhanina MO, Kovalenko EI, Chudakov DM.   +2 more
europepmc   +1 more source

Mechanisms of action and clinical development of elotuzumab [PDF]

, 2017
Colonna, Marco, Ritchie, David
core   +2 more sources

Inhibitory NK receptor expression associates with altered antimalarial function of γδ T cells. [PDF]

PLoS Pathog
Olive ME, Callaway PC, Ilala M, Levan J, Acevedo GR, Nankya F, Arinaitwe E, Rek J, Jagannathan P, Dorsey G, Kamya MR, Feeney ME.   +11 more
europepmc   +1 more source

Examining the association between fetal HLA-C, maternal KIR haplotypes and birth weight. [PDF]

PLoS Genet
Decina CS, Warrington NM, Beaumont RN, Bian B, Brito Nunes C, Wang G, Lowe WL, Squire D, Vukcevic D, Leslie S, Freathy RM, Evans DM.   +11 more
europepmc   +1 more source

Integrative Roles of NK Receptors and γδ TCRs in γδ T Cell-Mediated Cancer Immunity. [PDF]

Immune Netw
Oh WJ, Cho H, Dahanayake TK, Kim TJ.
europepmc   +1 more source