Results 121 to 130 of about 26,234 (229)

Effect of NK cell receptor genetic variation on allogeneic stem cell transplantation outcome and in vitro NK cell cytotoxicity

open access: yesScientific Reports
Natural killer (NK) cells recognize and may kill malignant cells via their cell surface receptors. Killer cell immunoglobulin-like receptor (KIR) genotypes of donors have been reported to adjust the risk of relapse after allogeneic stem cell ...
Julia Nihtilä   +16 more
doaj   +1 more source

Killer Immunoglobulin-Like Receptor Profiles are not Associated with risk of Amoxicillin-Clavulanate-Induced Liver Injury in Spanish Patients

open access: yesFrontiers in Pharmacology, 2016
Natural killer cells are an integral part of the immune system and represent a large proportion of the lymphocyte population in the liver. The activity of these cells is regulated by various cell surface receptors, such as killer Ig-like receptors (KIR ...
Camilla Stephens   +12 more
doaj   +1 more source

Killer Cell Immunoglobulin-like Receptors (KIR) and Human Leucocyte Antigen C (HLA-C) Increase the Risk of Long-Term Chronic Liver Graft Rejection. [PDF]

open access: yesInt J Mol Sci, 2022
Legaz I   +7 more
europepmc   +1 more source

Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy [PDF]

open access: yes, 2017
Hypertension during pregnancy is the most common medical condition encountered during gestation. Despite this, knowledge of the mechanisms that underlie the disease and the development of new therapies are limited.
Cornelius, Denise C.   +3 more
core   +1 more source

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
The incubation of primary astrocytes with fAuNCs‐BSA induces: (A) long‐term effects including fAuNCs‐BSA internalization, red cell fluorescence, differentiation, upregulation of Ca2+ signaling, Cl‐current, and cell volume regulation. B) Short‐term (200 ms) stimulation with UV LED light increases in Ca2+ signaling and inhibition of K+ current. Astrocyte
Roberta Fabbri   +21 more
wiley   +1 more source

Association of paternal HLA-C and maternal killer-cell immunoglobulin-like receptor genotypes in the development of autism

open access: yesFrontiers in Pediatrics, 2016
Natural killer (NK) cells belong to the innate immunity system. Their activity is regulated by inhibitory and activating receptors. The major family of inhibitory receptors is the Killer immunoglobulin-like receptors (KIRs) which recognize MHC class I ...
Moriya Gamliel   +4 more
doaj   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang   +4 more
wiley   +1 more source

Improved Survival with Inhibitory Killer Immunoglobulin Receptor (KIR) Gene Mismatches and KIR Haplotype B Donors after Nonmyeloablative, HLA-Haploidentical Bone Marrow Transplantation

open access: yesBiology of Blood and Marrow Transplantation, 2010
Natural killer (NK) cell alloreactivity, which may contribute to the graft-versus-leukemia (GVL) effect of allogeneic hematopoietic stem cell transplantation (HSCT), is influenced by the interaction of killer-cell immunoglobulin-like receptors (KIRs) on donor NK cells and their ligands, human leukocyte antigen (HLA) class I molecules on recipient ...
Symons, Heather J.   +5 more
openaire   +2 more sources

The importance of the interactions between KIRs and HLA ligands in the development of human autoimmune and viral diseases [PDF]

open access: yes, 2017
Killer immunoglobulin-like receptors (KIRs) regulate the activation of natural killer cells through their interaction with human leucocyte antigens (HLA).
Accardi Giulia   +5 more
core  

A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]

open access: yes, 2007
The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

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