Results 121 to 130 of about 560,467 (222)
PNH is a haematopoietic disorder characterized by expansion of PIG-A-defective progenitor(s). Immune-dependent mechanisms, likely involving a deranged T-cell-dependent autoimmune response have been consistently associated with the selection/dominance of
RUGGIERO, GIUSEPPINA +22 more
core +1 more source
Relevance of KIR gene polymorphisms in bone marrow transplantation outcome
International audienceNatural Killer (NK) cells may be involved both in allogeneic bone marrow transplantation (BMT) rejection and graft-versus-host disease (GVHD).
Folléa, Gilles +23 more
core +1 more source
Association of KIR-HLA interactions with diseases
The killer cell immunoglobulin-like receptors (KIR) are a recently discovered family of activating and inhibitory receptors which control natural killer (NK) cell function. KIR exist as a diverse family of receptors that have evolved rapidly by both gene
Tahereh Mousavi +3 more
core
KIR on the cusp of modern immunogenetics
Killer Immunoglobulin-like Receptors (KIR) and their Human Leukocyte Antigen (HLA) ligands play a central role in immunity and human health. These molecules are encoded by gene families with copy number variation, extreme levels of sequence diversity and
core +2 more sources
Table_1_Extensive Alternative Splicing of KIR Transcripts.XLSX
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules.
Jesse Bruijnesteijn (6038990) +7 more
core +1 more source
Institutes of Brain Science and Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology, Shanghai Key Laboratory of Visual Impairment and Restoration, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032 ...
Xue-Yan Li +8 more
core +1 more source
Data_Sheet_1_Extensive Alternative Splicing of KIR Transcripts.PDF
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules.
Jesse Bruijnesteijn (6038990) +7 more
core +1 more source
Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes
The immune and reproductive functions of human NK cells are regulated by interactions of the C1 and C2 epitopes of HLA-C with C1-specific and C2-specific lineage III killer cell Ig-like receptors (KIR). This rapidly evolving and diverse system of ligands
Lisbeth A. Guethlein +8 more
core +1 more source
Hanging in the balance: KIR and their role in disease
The killer cell immunoglobulin-like receptors (KIR) are a recently discovered family of activating and inhibitory receptors that control natural killer (NK) cell function.
Khakoo, Salim I. +2 more
core +1 more source
KIR-mediated NK education mediates KIR-associated Crohn's disease susceptibility
Purpose/Objective: Natural Killer (NK) cells are innate effector lymphocytes in the host response to infections and tumors through a variety of activating and inhibitory receptors. NK cells require education by self-human leukocyte antigen (HLA) class
McGovern, Dermot +6 more
core

