Results 111 to 120 of about 560,467 (222)

Altered neural electrophysiological properties in the anterior cingulate cortex in a mouse model of Prader‐Willi syndrome

The Journal of Physiology, Volume 604, Issue 17, Page 7313-7336, 1 September 2026.
Abstract figure legend Prader‐Willi syndrome (PWS) originates from deficiencies in chromosome 15q11‐13 region clustering around a critical region containing multiple‐repeat non‐coding RNA gene Snord116, resulting in metabolic and behavioural abnormalities leading to hyperphagia and obesity.
Volodymyr Rybalchenko, Ryan Butler
wiley   +1 more source

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC

Frontiers in Immunology, 2019
Natural killer (NK) cells have diverse roles in hominid immunity and reproduction. Modulating these functions are the interactions between major histocompatibility complex (MHC) class I molecules that are ligands for two NK cell surface receptor types ...
Emily E. Wroblewski, Peter Parham, Lisbeth A. Guethlein   +2 more
doaj   +1 more source

Association of killer immunoglobulin-like receptor genotypes and haplotypes with acute lymphoblastic leukemia risk

Innate Immunity
Background Killer immunoglobulin-like receptors (KIRs) are key molecules used by natural killer (NK) cells to interact with target cells. These receptors exhibit extensive genotypic polymorphism which has been associated with varying outcomes in immune ...
Jameel Al-Tamimi, Suliman Alomar, Ali Aljuaimlani, Lamjed Mansour   +3 more
doaj   +1 more source

kir‐mapper: A Toolkit for Killer‐Cell Immunoglobulin‐Like Receptor (KIR) Genotyping From Short‐Read Second‐Generation Sequencing Data

HLA
ABSTRACTKiller cell immunoglobulin‐like receptors (KIRs) regulate natural killer (NK) cell responses by activating or inhibiting their functions. Genotyping KIR genes from short‐read second‐generation sequencing data remains challenging as cross‐alignments among genes and alignment failure arise from gene similarities and extreme polymorphism.
Erick C. Castelli, Raphaela Neto Pereira, Gabriela Sato Paes, Heloisa S. Andrade, Marcel Rodrigues Ferreira, Ícaro Scalisse de Freitas Santos, Nicolas Vince, Nicholas R. Pollock, Paul J. Norman, Diogo Meyer   +9 more
openaire   +3 more sources

Autologous and allogeneic HLA KIR ligand environments and activating KIR control KIR NK-cell functions

, 2008
International audienceNK-cell function is regulated by a balance between inhibitory and activating killer cell immunoglobulin-like receptors (KIR) that specifically recognize HLA class I molecules.
Folléa, Gilles, Véronique Sébille, Katia Gagne, Clémenceau, Béatrice, Laure Denis, Gilles Folléa, Béatrice Clémenceau, Maelig Morvan, Morvan, Maelig, Gagne, Katia, Kerdudou, Nolwenn, Aurore Perrin, Denis, Laure, Catherine Willem, Jean-Denis Bignon, Christelle Retière, David, Gaëlle, Perrin, Aurore, Gaëlle David, Nolwenn Kerdudou, Bignon, Jean-Denis, Sébille, Véronique, Retiere, Christelle, Willem, Catherine   +23 more
core   +1 more source

NKG2D and KIR Receptors and Their Role in Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia

, 2023
NKG2D and KIR receptors and their role in allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia ABSTRACT NK cells (from Natural Killer) play an important role in the fight against viral infections or cancer.
Machuldová, Alena
core  

Killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen-C (HLA-C) allorecognition patterns in women with endometriosis. [PDF]

Sci Rep, 2020
Chou YC, Chen CH, Chen MJ, Chang CW, Chen PH, Yu MH, Chen YJ, Tsai EM, Yang PS, Lin SY, Tzeng CR.   +10 more
europepmc   +1 more source

KIR channels tune electrical communication in cerebral arteries

, 2016
The conducted vasomotor response reflects electrical communication in the arterial wall and the distance signals spread is regulated by three factors including resident ion channels. This study defined the role of inward-rectifying K(+) channels (KIR) in
Hald, Bjorn O, Hald, Bjorn O., Marrelli, Sean P, Samson, Nina C., Samson, Nina C, Sancho, Maria, Hashad, Ahmed M., Hashad, Ahmed M, Sancho González, María, Welsh, Donald G., Marrelli, Sean P., Brett, Suzanne E., Welsh, Donald G, Brett, Suzanne E   +13 more
core   +1 more source

Killer Cell Immunoglobulin-like Receptors and their Ligands

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
<p>The Natural killer (NK) cells are a subset of lymphocytes comprising around 10% of total lymphocytes in peripheral blood. Due to their role in the innate response, NK cells provide a ‘first line of defense’ against infectious agents and cancer ...
F Shahsavar
doaj  

IPD - the Immuno Polymorphism Database [PDF]

, 2005
The Immuno Polymorphism Database (IPD) (http://www.ebi.ac.uk/ipd/) is a set of specialist databases related to the study of polymorphic genes in the immune system.
Marsh, S.G.E., Robinson, J., Waller, M.J., Stoehr, P.   +3 more
core