Results 91 to 100 of about 560,467 (222)

Killer Cell Immunoglobulin-like Receptors and their Ligands [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
The Natural killer (NK) cells are a subset of lymphocytes comprising around 10% of total lymphocytes in peripheral blood. Due to their role in the innate response, NK cells provide a ‘first line of defense’ against infectious agents and cancer and are ...
Tajik N., Shahsavar F., Entezami K.
doaj   +2 more sources

Distribution of killer cell immunoglobulin-like receptors genes in the Italian Caucasian population

Journal of Translational Medicine, 2006
Background Killer cell immunoglobulin-like receptors (KIRs) are a family of inhibitory and activatory receptors that are expressed by most natural killer (NK) cells. The KIR gene family is polymorphic: genomic diversity is achieved through differences in
Mariani M, Malagoli A, Lombardo C, Iannone AM, Frison S, Dametto E, Cosentini E, Chiesa A, Carcassi C, Martinetti M, Cuccia MC, Testi M, Bontadini A, Mariotti L, Mascaretti L, Mele L, Miotti V, Nesci S, Ozzella G, Piancatelli D, Romeo G, Tagliaferri C, Vatta S, Andreani M, Conte R   +24 more
doaj   +1 more source

Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes

, 2003
Using monoclonal antibodies (mAbs) specific for different natural killer (NK) receptors, we studied the lymphocyte population from 18 patients with NK-type lymphoproliferative disease of granular lymphocytes (LDGL).
ZAMBELLO R, TRENTIN L, SEMENZATO G, AGOSTINI, CARLO, CASTRICONI R, CASTRICONI, ROBERTA, FALCO M, CARLOMAGNO S, CAROLLO D, CARLOMAGNO, SIMONA, SEMENZATO, GIANPIETRO CARLO, CANNAS G, VITALE M., MORETTA, ALESSANDRO, DELLA CHIESA M, DELLA CHIESA, MARIELLA, CABRELLE A, CABRELLE, ANNA, MORETTA A, ZAMBELLO, RENATO, TRENTIN, LIVIO, LAMY T, AGOSTINI C   +22 more
core   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

KIR genotypic diversity in Portuguese and analysis of KIR gene allocation after allogeneic hematopoietic stem cell transplantation

, 2016
The diversity of killer-cell immunoglobulin-like receptors (KIR) genes was evaluated in Portuguese and the observed genotypic profiles were found related to the ones reported in European populations.
Sanchez-Mazas, Alicia, Ligeiro, D., Buhler, Stéphane, Trindade, H., da Silva, M. Gomes, Abecasis, M., Abade, O.   +6 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, Volume 600, Issue 17, Page 2437-2450, September 2026.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Killer Immunoglobulin-Like Receptor Profiles are not Associated with risk of Amoxicillin-Clavulanate-Induced Liver Injury in Spanish Patients

Frontiers in Pharmacology, 2016
Natural killer cells are an integral part of the immune system and represent a large proportion of the lymphocyte population in the liver. The activity of these cells is regulated by various cell surface receptors, such as killer Ig-like receptors (KIR ...
Camilla Stephens, Antonia Moreno-Casares, Miguel-Ángel López-Nevot, Miren García-Cortés, Inmaculada Medina-Cáliz, Hacibe Hallal, German Soriano, Eva Roman, Eva Roman, Francisco Ruiz-Cabello, Manuel Romero-Gomez, M Isabel Lucena, Raúl J Andrade   +12 more
doaj   +1 more source

Killer Cell Immunoglobulin-like Receptors (KIR) and Human Leucocyte Antigen C (HLA-C) Increase the Risk of Long-Term Chronic Liver Graft Rejection. [PDF]

Int J Mol Sci, 2022
Legaz I, Bolarín JM, Campillo JA, Moya-Quiles MR, Miras M, Muro M, Minguela A, Álvarez-López MR.   +7 more
europepmc   +1 more source

Does Japanʼs Aid Promote the Economic Growth of Pacific Island Countries?

Asia &the Pacific Policy Studies, Volume 13, Issue 3, September 2026.
ABSTRACT Pacific Island countries (PICs) are among the worldʼs most aid‐dependent nations. This study examines relations between Japanʼs aid and the economic growth of 13 PICs during 2000–2023. After evaluating overall effects of Japanʼs aid, specific types are analysed: economic, social, production, and multi‐sector aid.
Wesley Steve Aru
wiley   +1 more source

The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution

BMC Evolutionary Biology, 2008
Background Recent studies have revealed an unexpected diversity of domain architecture among FcR-like receptors that presumably fulfill regulatory functions in the immune system.
Najakshin Alexander M, Mechetina Ludmila V, Erilova Aleksandra Y, Ramanayake Thaminda, Guselnikov Sergey V, Robert Jacques, Taranin Alexander V   +6 more
doaj   +1 more source