Results 71 to 80 of about 560,467 (222)
Natural killer cells and cancer: Regulation by the killer cell Ig-like receptors (KIR) [PDF]
Cancer Biology & Therapy, 2009 Natural killer (NK) cells are innate immune effector cells that make up approximately 10-15% of the peripheral blood lymphocytes in humans and are primarily involved in immunosurveillance to eliminate transformed and virally-infected cells. They were originally defined by their ability to spontaneously eliminate rare cells lacking expression of class I
Amanda K. PURDY, Kerry S. CAMPBELL
openaire +4 more sources
Cutaneous lymphomas – an update
Histopathology, EarlyView.Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley +1 more source
Natural killer cell immunity after transplantation
Swiss Medical Weekly, 2012 Transplantation immunology has traditionally focused on adaptive, i.e., T- and B-cell reactions. More recently, natural killer (NK) cells were also recognised as playing an important role after transplantation of solid organs and haematopoietic ...
Grzegorz Terszowski +2 more
doaj +1 more source
The impact of KIR/HLA genes on the risk of developing multibacillary leprosy. [PDF]
PLoS Neglected Tropical Diseases, 2019 BACKGROUND:Killer-cell immunoglobulin-like receptors (KIRs) are a group of regulatory molecules able to activate or inhibit natural killer cells upon interaction with human leukocyte antigen (HLA) class I molecules.
Hugo Vicentin Alves +9 more
doaj +1 more source
Análise epidemiológica e de associação dos genes kir com artrite reumatoide [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biologia Celular e do DesenvolvimentoA artrite reumatoide (AR) é uma doença autoimune caracterizada por inflamação crônica que ...
Farias, Ticiana Della Justina
core
HLA and KIR Frequencies in Sicilian Centenarians [PDF]
, 2010 Several studies suggest that human longevity appears to be linked inextricably with optimal functioning of the immune system, suggesting that specific genetic determinants may reside in loci that regulate the immune response, as human leukocyte antigen
LIO, Domenico +5 more
core +1 more source
The Turkey Ig-like receptor family: identification, expression and function. [PDF]
, 2012 The chicken leukocyte receptor complex located on microchromosome 31 encodes the chicken Ig-like receptors (CHIR), a vastly expanded gene family which can be further divided into three subgroups: activating CHIR-A, bifunctional CHIR-AB and inhibitory ...
Windau, Katharina +7 more
core +2 more sources
Extensive Alternative Splicing of KIR Transcripts
Frontiers in Immunology, 2018 The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules.
Jesse Bruijnesteijn +8 more
doaj +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
The Journal of Physiology, EarlyView.Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
Frontiers in Immunology, 2013 Killer cell immunoglobulin-like receptors (KIRs) are a family of cell surface inhibitory or activating receptors expressed on natural killer cells and some subpopulations of T lymphocytes.
Piotr eKusnierczyk
doaj +1 more source