Results 51 to 60 of about 560,467 (222)

Nasal Epithelial Immune Signatures Are Associated With Age‐Dependent Asthma Trajectories in Early Life

open access: yesAllergy, EarlyView.
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth   +71 more
wiley   +1 more source

Lack of expression of inhibitory KIR3DL1 receptor in patients with natural killer cell-type lymphoproliferative disease of granular lymphocytes

open access: yesHaematologica, 2010
Background Natural killer cell-type lymphoproliferative disease of granular lymphocytes is a disorder characterized by chronic proliferation of CD3−CD16+ granular lymphocytes.
Cristina Gattazzo   +13 more
doaj   +1 more source

BRET-Based Approaches for Ion Channels: Emerging Applications and Future Directions. [PDF]

open access: yesArch Pharm (Weinheim)
Bioluminescence resonance energy transfer (BRET) is a versatile method for studying ligand–protein interactions. Its compatibility with high‐throughput screening and real‐time kinetics has made it widely used in drug discovery. Here, we summarize recent applications of BRET‐based methods for studying ligand binding to ion channels, highlighting key ...
Kock N   +6 more
europepmc   +2 more sources

Optimizing cord blood unit selection to improve survival after single‐unit unrelated cord blood transplantation for adult myelodysplastic syndrome

open access: yesBritish Journal of Haematology, EarlyView.
Summary Unrelated cord blood transplantation (CBT) is an important alternative donor option for adult patients with myelodysplastic syndrome (MDS); however, the prognostic significance of cord blood unit characteristics following CBT remains unclear and may vary according to disease risk.
Takaaki Konuma   +23 more
wiley   +1 more source

The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling

open access: yesCell Reports, 2016
Super-resolution microscopy has revealed that immune cell receptors are organized in nanoscale clusters at cell surfaces and immune synapses. However, mechanisms and functions for this nanoscale organization remain unclear. Here, we used super-resolution
Anna Oszmiana   +6 more
doaj   +1 more source

KIR gene content in amerindians indicates influence of demographic factors. [PDF]

open access: yesPLoS ONE, 2013
Although the KIR gene content polymorphism has been studied worldwide, only a few isolated or Amerindian populations have been analyzed. This extremely diverse gene family codifies receptors that are expressed mainly in NK cells and bind HLA class I ...
Danillo Gardenal Augusto   +4 more
doaj   +1 more source

KIR-HLA compound genotype distribution.

open access: yes, 2018
KIR-HLA compound genotype distribution.
Yonghong Zhang (20918)   +5 more
core   +1 more source

Learning curve of Versius‐assisted radical prostatectomy: role of prior experience and proctoring

open access: yesBJU International, EarlyView.
Objective To assess the learning curve for radical prostatectomy (RP) with the Versius system (CMR Surgical, Cambridge, UK) and evaluate the transfer of skills from previous robotic and laparoscopic practice. Subjects, Patients and Methods This prospective cohort study included patients with localised prostate cancer undergoing Versius‐assisted RP ...
Guillermo Fernández‐Conejo   +11 more
wiley   +1 more source

Donor and host coexpressing KIR ligands promote NK education after allogeneic hematopoietic stem cell transplantation

open access: yesBlood Advances, 2019
: The rate and extent of natural killer (NK)–cell education after hematopoietic cell transplantation correlates with leukemia control. To study the effect of donor and host HLA on NK-cell reconstitution, single killer-cell immunoglobulin-like receptor ...
Xiang-Yu Zhao   +11 more
doaj   +1 more source

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]

open access: yes, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Meyer, Claus   +23 more
core   +1 more source

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