Results 101 to 110 of about 77,479 (303)
Annals of Neurology, EarlyView.Objective Our goal was to examine whether pre‐diagnostic plasma carotenoids and tocopherols are associated with amyotrophic lateral sclerosis (ALS). Methods A nested case–control study within 4 United States cohorts, where 154 participants with pre‐diagnostic blood‐draw, were diagnosed during follow‐up with amyotrophic lateral sclerosis (ALS). Controls
Éilis J. O'Reilly +7 more
wiley +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
Mechanisms of cytokine release induced by electronegative LDL in monocytes. The role of ceramide and the receptors CD14-TLR4 [PDF]
, 2014 L'LDL electronegativa (LDL(-)) és una LDL modificada present en circulació amb propietats inflamatòries incloent la inducció de l'alliberament de citoquines en cèl·lules relacionades amb l'arteriosclerosi, tals com monòcits i cèl·lules endotelials.
Estruch, Montserrat +1 more
core +2 more sources
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Atherosclerosis is the chronic inflammatory disease, and inflammation-elicited endothelial activation is an early event in the development of atherosclerosis.
Yun Kuang +5 more
doaj +1 more source
Efeito da suplementação de ácidos graxos ômega-3 no perfil lipídico e mediadores inflamatórios de pacientes com insuficiência cardíaca submetidos a exercício físico supervisionado [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2013.A insuficiência cardíaca (IC) é um estado patológico das fases avançadas das cardiopatias, podendo ...
Casagrande, Fernanda da Silva
core
The Functional Characterization of PCSK9's Binding Interactions with LDL and the LDL Receptor
, 2020 Elevated plasma cholesterol is a risk factor for cardiovascular disease. Proprotein convertase subtilisin/kexin type 9 (PCSK9) hinders the uptake of low-density lipoprotein cholesterol (LDL-c) by mediating degradation of LDL receptors (LDLRs) in the ...
Matyas, Angela
core +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Drug Delivery, 2018 Therapeutic outcome for the treatment of glioma was often limited due to the non-targeted nature and low permeability of drugs across the blood-brain barrier (BBB).
Meng Liang +17 more
doaj +1 more source
New lipid therapies: PCSK9 inhibitors
Journal of Clinical and Translational Endocrinology Case Reports, 2016 Pharmacologic therapy reduces cardiovascular risk in a variety of primary and secondary prevention clinical situations in addition to lifestyle modifications. Low density lipoprotein cholesterol (LDL-C) is a key mediator of atherogenesis.
Farah Meah, DO +4 more
doaj +1 more source
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi +2 more
wiley +1 more source