Results 131 to 140 of about 73,504 (258)

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Cholesterol-Inflammation Fusion Hypothesis in Atherosclerosis: An Evolving Paradigm in Pathogenesis and Therapy. [PDF]

JACC Asia
Zeng RX, Li S, Li JJ.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Very low-density lipoprotein and the human health. [PDF]

World J Exp Med
Bharadwaj A, Taneja M, Dubey S, Saxena A.   +3 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Exploring sex bias in cardiometabolic diseases. [PDF]

Lipids Health Dis
Guillemette T, Rhainds D, Robert O, Mounier C.   +3 more
europepmc   +1 more source

Glucolipid Metabolic Disorders and <i>Helicobacter pylori</i> Infection. [PDF]

Int J Endocrinol
Yuan J, Xiong P, Zhou Z, Wu J, Wu B, Wang B, Guo J.   +6 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Dual Receptor Targeting Ensures Uptake and Anticancer Efficacy of Low-Density Lipoprotein-Docosahexaenoic Acid Nanoparticles Across Breast Cancer Cell Subtypes. [PDF]

Breast Cancer (Dove Med Press)
Bower J, Anwar A, Chaudhary J, Chen Z, Schumacher M, Debose-Boyd R, Corbin IR.   +6 more
europepmc   +1 more source

Practices, barriers, and opportunities for dietitians‐nutrionists in critical care in latin america: A cross‐sectional study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Dietitians–nutritionists (DNs) play a key role in intensive care units (ICUs), yet their scope of practice varies across settings. This study aimed to describe the professional practices of DNs working in ICUs in Latin America and to identify factors associated with their level of professional activity.
Mirta Crovetto, Solange Parra‐Soto, Samuel Durán‐Aguero, Karla Cordón‐Arrivillaga, Marisa Canicoba, Leslie Landaeta‐Díaz, Jhon Jairo Bejarano, Saby Mauricio, Edna J. Nava‐González, Valeria Carpio‐Arias, Sheila Cerezo, Sonia Ivankovich, Alfonsina Ortiz, Beatriz Nuñez‐Martinez, Eliana Romina Meza‐Miranda, Gertrudis M Adrianza de Baptista, Marisela Morales, Melissa Miranda‐Durán, Frank Carrera‐Gil   +18 more
wiley   +1 more source